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Case Study: Perceptive Engineering
3 July 2015 • Author(s): Perceptive Engineering
Perceptive Engineering discusses a two year collaborative R&D project it undertook to address challenges associated with the new generation of reactor systems used in production.
A new generation of continuous small-scale reactors that will enable manufacturers of high-value, low volume products to move away from traditional batch processes, has recently come onto the market.
These micro reactors can be used in parallel, to achieve production scale-up without the associated chemical engineering problems. The major benefit of these reactors is the flexibility they offer, i.e., the ability to manufacture a number of products using a single reactor by rapidly adjusting the operating conditions, with little waste material generated during the transition.
Typical benefits of such systems include a waste reduction of 10-15%, energy reduction of 40-70% and solvent process inventory that can be as low as 10% of volume in an equivalent batch process.
Currently these reactors require high levels of manual intervention, to identify suitable operating conditions and adjust the process as needed to maintain final product quality. This can be challenging; the design of the reactors, and the ancillary equipment they require, often result in complex system interactions.
ABB Analytical Measurement ACD/Labs ADInstruments Ltd Advanced Analytical Technologies GmbH Analytik Jena AG Astell Scientific Ltd B&W Tek Bachem AG Bibby Scientific Limited Bio-Rad Laboratories BioNavis Ltd Biopharma Group Black Swan Analysis Limited CAPSUGEL NV Charles Ischi AG | Kraemer Elektronik Cherwell Laboratories CI Precision Cobalt Light Systems Coulter Partners CPC Biotech srl Dassault Systèmes BIOVIA DiscoverX Edinburgh Instruments Enterprise System Partners (ESP) Eurofins BioPharma Product Testing EUROGENTEC F.P.S. Food and Pharma Systems Srl GE Analytical Instruments IDBS JEOL Europe L.B. Bohle Maschinen + Verfahren GmbH Lab M Ltd. LabWare Linkam Scientific Instruments Limited MA Business Metrohm Molins Technologies Multicore Dynamics Ltd Nanosurf New England Biolabs, Inc. Ocean Optics Panasonic Biomedical Sales Europe B.V. PerkinElmer Inc ReAgent Russell Finex Limited Source BioScience Takara Clontech Tornado Spectral Systems Tuttnauer Viavi Solutions, Inc Watson-Marlow Fluid Technology Group Wickham Laboratories Limited Xylem Analytics YMC Europe GmbH Yusen Logistics