- Cancer Biology & Biomarkers
- Chromatography & Mass Spectrometry
- Contract Research, Clinical Trials and Outsourcing
- Drug Discovery
- Drug Targets
- Flow Cytometry
- Informatics & Lab Automation
- Ingredients, Excipients and Dosages
- Microbiology & RMMs
- NIR, PAT & QbD
- Raman Spectroscopy
- Screening, Assays & High-Content Analysis
- Thermal Processing
Soliris could drive myasthenia gravis treatment market value beyond $550 million by 2024, says GlobalData
14 July 2015 • Author: Victoria White
The global market for myasthenia gravis therapeutics is anticipated to more than treble in value from $146.4 million in 2014 to $550.4 million by 2024, driven primarily by the potential entry of Alexion’s Soliris during the forecast period, according to research and consulting firm GlobalData.
The Company’s latest report, OpportunityAnalyzer: Myasthenia Gravis – Opportunity Analysis and Forecasts to 2024,states that while only a small percentage of refractory myasthenia gravis patients would receive Soliris across the seven major markets of the US, France, Germany, Italy, Spain, UK, and Japan, the drug has the potential to have a notable impact on growth due to its premium pricing.
Melina Reisenberg, Ph.D., GlobalData’s Analyst covering Neurology, says Soliris is expected to launch in the US in 2018, followed by its entry in the five European countries (5EU) and Japan in 2019 and 2020, respectively.
Reisenberg explained, “Patients with refractory myasthenia gravis have a significant need for new targeted treatment options, as they have been unable to achieve disease control with the available therapies.
“The results from a Soliris trial in myasthenia gravis patients were promising overall. However, due to the considerable cost of Soliris, reimbursement difficulties are expected and might prevent the drug from fulfilling its commercial potential, especially in the 5EU.”
Early-stage pipeline for myasthenia gravis treatments is very limited
Despite the current market being dominated by generics with a low annual cost of therapy, GlobalData forecasts peak year sales of $388.9 million for Soliris across the seven major markets in 2024, providing the treatment is approved and reimbursed in all markets.
The analyst adds that while opportunities will remain following the anticipated introduction of pipeline drugs, which target a broader myasthenia gravis patient population, including non-refractory patients, the early-stage pipeline is very limited.
Reisenberg continued, “Two other compounds targeting the same signalling pathway as Soliris have the potential to be developed for myasthenia gravis and could offer a more cost-effective alternative to monoclonal antibodies.
“However, neither Alnylam’s ALN-CC5 nor Akari Therapeutics’ (formerly Volution Immuno Pharmaceuticals) Coversin are likely to be investigated as treatments for myasthenia gravis in the near future.”
ABB Analytical Measurement ACD/Labs ADInstruments Ltd Advanced Analytical Technologies GmbH Analytik Jena AG Astell Scientific Ltd B&W Tek Bachem AG Bibby Scientific Limited Bio-Rad Laboratories BioNavis Ltd Biopharma Group Black Swan Analysis Limited Butterworth Laboratories Ltd CAPSUGEL NV Charles Ischi AG | Kraemer Elektronik Cherwell Laboratories CI Precision Cobalt Light Systems Coulter Partners CPC Biotech srl Dassault Systèmes BIOVIA DiscoverX Edinburgh Instruments Enterprise System Partners (ESP) Eurofins BioPharma Product Testing EUROGENTEC F.P.S. Food and Pharma Systems Srl GE Analytical Instruments IDBS JEOL Europe Kaiser Optical Systems Inc. L.B. Bohle Maschinen + Verfahren GmbH Lab M Ltd. LabWare Linkam Scientific Instruments Limited Lonza MA Business Metrohm Molins Technologies Multicore Dynamics Ltd Nanosurf New England Biolabs, Inc. Ocean Optics Panasonic Biomedical Sales Europe B.V. Peak Scientific ReAgent Russell Finex Limited Sentronic GmbH Source BioScience Takara Clontech Tornado Spectral Systems Tuttnauer Viavi Solutions, Inc Watson-Marlow Fluid Technology Group Wickham Laboratories Limited WITec GmbH Xylem Analytics YMC Europe GmbH Yusen Logistics