- Cancer Biology & Biomarkers
- Chromatography & Mass Spectrometry
- Contract Research, Clinical Trials and Outsourcing
- Drug Discovery
- Drug Targets
- Flow Cytometry
- Informatics & Lab Automation
- Ingredients, Excipients and Dosages
- Microbiology & RMMs
- NIR, PAT & QbD
- Raman Spectroscopy
- Screening, Assays & High-Content Analysis
- Thermal Processing
NICE approves CDF drugs for routine NHS use
24 August 2016 • Author: National Institute for Health and Care Excellence (NICE)
The National Institute for Health and Care Excellence (NICE) issued final guidance recommending two drugs for routine use within the NHS:
- Bosutinib (Bosulif, Pfizer) for treating some patients with leukaemia
- Pemetrexed (Alimta, Eli Lilly) for treating some patients with lung cancer
Both of these drugs were previously available on the Cancer Drugs Fund (CDF).
Following the decision to reform the CDF, NICE has been assessing the cost and clinical effectiveness of drugs currently in the old CDF.
Both companies submitted additional cost analyses and offered the NHS a discounted price for their drugs as part of this reappraisal process, which meant that both drugs are now considered value for money.
Professor Carole Longson, Director of the Centre for Health Technology Evaluation at NICE, said, “It’s great to see that companies are engaging with our CDF reconsideration process in a constructive way, resulting in these positive recommendations. Patients with chronic myeloid leukaemia and lung cancer will now be reassured that these drugs are available for routine NHS use.”
“This is good news. As these drugs move into routine budgets, CDF funding can be freed up for other new and innovative cancer treatments.”
The NHS now has a legal obligation to make both drugs available to all eligible people who need it, if they and their doctor agree it is the right treatment.
Bosutinib is used to treat chronic myeloid leukaemia in people who have a genetic abnormality known as the Philadelphia chromosome which causes the overproduction of white blood cells. Bosutinib is only recommended when other treatments no longer work or are otherwise inappropriate.
Bosutinib costs around £45,000 per patient a year at its undiscounted price.
NICE originally published guidance not recommending bosutinib in 2013.
NICE already recommends pemetrexed as maintenance treatment for some people with advanced non-small-cell lung cancer. This new recommendation means that pemetrexed will now be routinely available as a maintenance treatment for a broader group of patients.
At its undiscounted price, pemetrexed costs around £11,500 per patient.
ABB Analytical Measurement ACD/Labs ADInstruments Ltd Advanced Analytical Technologies GmbH Analytik Jena AG Astell Scientific Ltd B&W Tek Bachem AG Bibby Scientific Limited Bio-Rad Laboratories BioNavis Ltd Biopharma Group Black Swan Analysis Limited Butterworth Laboratories Ltd CAPSUGEL NV Charles Ischi AG | Kraemer Elektronik Cherwell Laboratories CI Precision Cobalt Light Systems Coulter Partners CPC Biotech srl Dassault Systèmes BIOVIA DiscoverX Edinburgh Instruments Enterprise System Partners (ESP) Eurofins BioPharma Product Testing EUROGENTEC F.P.S. Food and Pharma Systems Srl GE Analytical Instruments IDBS JEOL Europe Kaiser Optical Systems Inc. L.B. Bohle Maschinen + Verfahren GmbH Lab M Ltd. LabWare Linkam Scientific Instruments Limited Lonza MA Business Metrohm Molins Technologies Multicore Dynamics Ltd Nanosurf New England Biolabs, Inc. Ocean Optics Panasonic Biomedical Sales Europe B.V. Peak Scientific ReAgent Russell Finex Limited Sentronic GmbH Source BioScience Takara Clontech Tornado Spectral Systems Tuttnauer Viavi Solutions, Inc Watson-Marlow Fluid Technology Group Wickham Laboratories Limited WITec GmbH Xylem Analytics YMC Europe GmbH Yusen Logistics