Streamlining with automation and robotics

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publication date: Sep 28, 2006

Protein crystallography has been embraced by the pharmaceutical industry to accelerate and rationalise the drug development process. In this role, success rates, throughput and turnaround times have become key competitive factors, and nearly every stage in the protein crystallography process has been targeted for automation using robotics and advanced software. However, it remains a challenge to combine available technologies, information infrastructure and work-flow protocols into a high throughput protein crystallography pipeline that takes account of the specific objectives and resources of an organisation. This article reviews process outlines and key decision making criteria to assist with the selection of a high throughput protein crystallography strategy.

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