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The human plasma proteome: A biomarker pool too deep to explore?

publication date: May 23, 2006
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The human blood plasma harbors treasure, which, like most treasures, is not easily attained, and finding it requires ingenuity, endurance and possibly a grain of luck. The blood plasma is the largest (most proteins) and deepest (widest dynamic range) of the human proteomes. In order to ‘triumph over’ it, it is necessary to overcome an enormous protein concentration range to finally be rewarded with the possible discovery of biomarkers. But is this a realistic challenge we are facing or is this plasma pool too deep to explore?



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