Ion chromatography (IC) allows the determination of trace ions using low capacity high efficiency columns possessing fixed ion exchange sites. Combined with suppressed conductivity detection, IC yields parts-per-billion detection of the seven common inorganic anions (F-, Cl-, NO2-, Br-, NO3-, HPO42- and SO42-) and to a lesser extent carboxylic acids, the six common cations (Li+, Na+, NH4+, K+, Mg2+ and Ca2+) and small amines.