Issue 6 2016

Issue #6 2016 – Digital version

Issue 6 2016 / 13 December 2016 / European Pharmaceutical Review

Read the free-to-view digital version of the latest issue of European Pharmaceutical Review…

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Raman In-Depth Focus

Issue 6 2016 / 13 December 2016 / European Pharmaceutical Review

In this supplement: Raman imaging evaluating counterfeit Cialis® tablets; analysis of capsule-based dry powder inhalers; Raman spectroscopy to authenticate medicines; Raman roundtable; as well as expert views…

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Application Notes & Whitepapers 2016

Issue 6 2016 / 13 December 2016 / European Pharmaceutical Review

With the huge range of processes involved in drug discovery and manufacture, it’s no wonder we had to create a separate magazine for this content – and as such we have a wide variety of applications…

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RMMs In-Depth Focus

Issue 6 2016 / 13 December 2016 / European Pharmaceutical Review

In this supplement: the role of statistical analysis in validating rapid microbiological methods; considerations when using RMMs for use in pharmaceutical microbiology; & RMMs roundtable…

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The prospects of medicinal plants in the treatment of breast cancer

Issue 6 2016 / 13 December 2016 / Osuntokun Oludare Temitope and Ogunleye Adewale Joseph, Adekunle Ajasin University

Plants that have known medicinal properties are plentiful in Africa, and primary healthcare in the developing world has, since ancient times, relied heavily on their cultivation and use. Increasingly, too, the uses and effects of medicinal plants are becoming of interest globally. One disease that could benefit from plant-based medicines is breast cancer, an illness that is endemic throughout the world. This article presents a comprehensive review of the literature for breast cancer, revealing the types, pathology and the different stages of the disease, before exploring the current prospects for treating breast cancer with medicinal plants found specifically in Nigeria. Promising early signs of anti-tumour activity have been seen with extracts derived from frankincense, holy basil and bitter melon, which suggests these plants could be cultivated for preventative or curative means.

Quality by Design for generic products: opportunities and challenges

Issue 6 2016 / 13 December 2016 / Patrick Crowley, Callum Consultancy & Sean McCrossen, IEXA100 Consulting

Quality by Design (QbD) precepts provide opportunities for enhancing efficiencies and reducing costs, especially for generic products. Over 80% of prescriptions dispensed in the United States in 2012 utilised generic dosage forms and it is unlikely that this proportion will increase to any extent because fewer innovative drugs are set to lose patent protection. Consequently, […]

Spray drying – various challenges, one solution?

Issue 6 2016 / 13 December 2016 / Nikki Whitfield, Quotient Clinical

Spray drying is a proven, flexible and scalable process used within the pharmaceutical industry to address a wide range of formulation and drug delivery challenges. Its versatility has been proven through applications to both small chemical and biopharmaceutical drugs for product delivery via multiple routes of administration. The technique is used to address stability challenges associated with temperature-sensitive molecules such as proteins and peptides, as well as providing innovative solutions for particle size critical applications such as inhaled drug delivery. In addition, the technology is now a primary formulation strategy to address an increasingly prevalent challenge in the industry: the successful oral delivery of poorly soluble compounds.

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The changing dynamics of the life sciences landscape

Issue 6 2016 / 13 December 2016 / Noel Gaule, Shire

The life sciences industry is dynamic and as we move towards 2020 and beyond, associated technologies will continue to converge. The forthcoming political, socio-economic and scientific era will throw up challenges, however, with these challenges will come great opportunities. As times change, pharmaceutical companies will need to employ innovative strategies for success. Importantly, patients will […]

 

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