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Special editions & supplements

Mass Spectrometry Supplement 2013

Mass Spectrometry: In-depth focus 2013

17 April 2013
Corticosteroids and mass spectrometry; latest applications using LC/MS3 (András Szeitz Faculty of Pharmaceutical Sciences, University of British Columbia)
Multi-analyte LC-MS/MS assays for the quantification of endogenous compounds during the development of drugs and companion diagnostics – the beauty and the beast (Uwe Christians, Jelena Klawitter and Jost Klawitter, iC42 Integrated Solutions for Systems Biology in Clinical Research and Development, Department of Anesthesiology, University of Colorado Denver)
Q&A (George McLeod, Market Manager, Pharmaceutical and Structural Chemistry, Bruker Daltonic sits down with Min Yang, UCL School of Pharmacy to answer his questions on mass spectrometry)
Show preview - European Lab Automation (ELA) 2013 Conference and Tradeshow
Show preview - ASMS Conference on Mass Spectrometry and Allied Topics

Stem Cells Supplement 2013

Stem Cells: In-depth focus 2013

17 April 2013
The promise held by induced pluripotent stem cells for research and regenerative medicine (Katharina Drews, Molecular Embryology and Aging Group, Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics / James Adjaye, Molecular Embryology and Aging Group, Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics & Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University)
Workshop preview – Cell based assays for screening
Cardiac stem cells (Annette Meeson, Institute of Genetic Medicine, Newcastle University)
Stem Cells Roundtable (Moderator: George E. Plopper, Professor, Department of Biology, Rensselaer Polytechnic Institute)
Show preview - ISSCR 11th Annual Meeting

Near Infrared (NIR) In-deptch focus 2013

Near Infrared Spectroscopy: In-depth focus 2013

18 February 2013
Validation methodologies of near infrared spectroscopy methods in pharmaceutical applications (Pierre-François Chavez, Charlotte De Bleye, Pierre-Yves Sacré, Eric Rozet, Philippe Hubert and Eric Ziemons - Laboratory of Analytical Chemistry, CIRM, Department of Pharmacy, University of Lie), Evaluating the influence of hopper geometry on radial and axial concentration profiles in flowing granular mixtures (Nicolas Abatzoglou, Eddy Castellanos Gil and Ryan Gosselin - Department of Chemical & Biotechnological Engineering, Pfizer Industrial Research Chair on PAT in Pharmaceutical Engineering, University of Sherbrooke)

Manufacturing & Packaging Supplement 2013

Pharmaceutical Manufacturing & Packaging: In-depth focus 2013

18 February 2013
The chemical safety assessment process for extractables and leachables associated with packaged pharmaceutical products (Dennis Jenke, Baxter Distinguished Scientist, Baxter Healthcare Corporation)
INTERPHEX 2013: Show preview


Drug Targets Supplement 2012

Drug Targets: In-depth focus 2012

11 December 2012
GPCR allosteric modulation: new opportunities and challenges for drug discovery (Patricia McDonald, Associate Scientific Director of Discovery Biology & Emmanuel Sturchler, Senior Scientist, Translational Research Institute, Scripps Florida)
Chloride channels and cardiac arrhythmia: novel therapeutic targets? (Dayue Darrel Duan, Laboratory of Cardiovascular Phenomics, the Department of Pharmacology, University of Nevada School of Medicine and colleagues)

qPCR Supplement 2012

qPCR: In-depth focus 2012

24 October 2012
Setting the bar (Mikael Kubista and Ales Tichopad, TATAA Biocenter and the Institute of Biotechnology, CAS, Medical Faculty Pilsen, Charles University of Prague)
Q & A - Mikael Kubista from the TATAA Biocenter poses five questions for Jay Brock, Senior Manager, Applications and Technical Support, USB® Life Science Reagents from Affymetrix
Not your grandfathers’ real-time PCR (Dirk P. Dittmer, Professor of Microbiology and Immunology and Member of Lineberger Comprehensive Cancer Center, University of North Carolina)

Raman Supplement 2012

Non-destructive material identification: In-depth focus 2012

24 October 2012
An implementation perspective on handheld Raman spectrometers for the verification of material identity (Bradley Diehl, Chi-Shi Chen, Bronwyn Grout, Jose Hernandez, Seamus O’Neill, Conor McSweeney, Jose Montenegro Alvarado and Mark Smith, Pfizer Inc)
Portable Raman spectroscopy for pharmaceutical counterfeit detection (Ravi Kalyanaraman, Michael Ribick and George Dobler, Bristol-Myers Squibb)
Ask the Expert

Microbiology-Series-2012-Part-1-100

Microbiology Series 2012 – Part 1

24 September 2012
We are pleased to present the first three articles in our series on Rapid Microbiological Methods written by Dr. Michael J. Miller:
New year, old challenges! - A discussion of how the acceptance of rapid microbiological methods (RMMs) continues to be hampered by misconceptions, misunderstandings and myths.
Rapid micro methods and EMA’s post approval change management protocol - A review of a relatively new process that the European Medicines Agency (EMA) launched that allows for the review and approval of RMM validation strategies before testing is initiated.
Rapid sterility testing and the impact of recent changes to the US Code of Federal Regulations - Recent changes in regulatory policy make it clear that RMMs for finished product sterility testing have a place in our industry, and it is the FDA that is leading the motivation for change.

Informatics In-depth focus 2012

Informatics – In-depth focus 2012

2 September 2012
DEVELOPING INFORMATICS FOR THE PHARMACEUTICAL INDUSTRY (Michael H. Elliott, CEO, Atrium Research & Consulting)
ROLLING OUT A BIOLOGY ELN AT UCB PHARMA (David Lee, Principal Scientist, Informatics, UCB)
ASK THE INFORMATICS EXPERTS (John Wise, Executive Director, Pistoia Alliance / Gerhard Noelken, Pfizer / Alexander Botzski, ELN Project Officer, VIB / Michael H. Elliott, CEO, Atrium Research & Consulting)
LABORATORY INFORMATICS – OUT OF THE FOG AND INTO THE CLOUD? (John Trigg, Director, phaseFour Informatics)
SHOW PREVIEW - 11th Annual ELNs & Advanced Laboratory Solutions

PAT Supplement 2012

In-depth focus – Process Analytical Technology (PAT)

6 July 2012
Process analytics experiences in biopharmaceutical manufacturing (Cenk Undey, Bryan Looze, Sinem Oruklu, Tony Wang and Rob Woolfenden, Process and Systems Analysis, Process and Product Engineering, Amgen)
Correlation between powder rheology data and processability in solid dosage form manufacturing (Erik Skibsted, Principal Scientist, Oral Protein Formulation, Novo Nordisk)
Ask the Expert - Expert industry users of process analytical technologies for pharmaceuticals pose questions for leading vendor experts of process analytical technology.

Stem Cells Supplement 2012

In-depth focus – Stem Cells

5 July 2012
STEM CELL THERAPIES: Assuring Safety (Michaela E. Sharpe, formerly Drug Safety Research and Development Portfolio Support, Pfizer)
ROLE OF PLURIPOTENT STEM CELLS IN NEUROTOXICOLOGY TESTING: Impacts and applied innovations (Mathurin Baquié, Igor Charvet, Luc Stoppini and Karl-Heinz Krause - University of Geneva)

In-Depth Focus: Mass Spectrometry

In-depth focus – Mass Spectrometry

25 April 2012
Mass spectrometry in drug discovery - Proteomics, small molecules and metablomics
Quantification of membrane drug transporters and application in drug discovery and development
Show preview - The 60th annual conference on Mass Spectrometry and Allied Topics
Anthony Bristow, AstraZeneca, poses the questions for our Mass Spectrometry Leaders Roundtable

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