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Freeze Drying
Functional Genomics
HCS
HTS
Ion Channel Drug Discovery
Ion Channel Electrophysiology
Ion Chromatography
Lab Automation
LIMS/ELNS
Lyophilization
Metabonomics
Microbiology
Microdialysis
Microdosing
Outsourcing
PAT
PCR
Personalised Medicine
Procurement
Project Management
Protein Crystallisation
Protein Crystallography
Proteomics
Raman Spectroscopy
Receptor Binding
RFID Technology
Rheology
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Russell Publishing Ltd
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Registered in England
No. 2709148
Registered office as above.
VAT No. GB 577 897847
Sitemap
Microbiology Classified Directories
bioMerieux
bioMérieux Delivers New Clean Room Range for Sterility Testing
Issue 4 2008
Issue 4 2008 Digital Magazine
Chromatin
Chromatin: cracking the chemical code
Oscar Trask
Achim Kirsch
Marc Bickle
Issue 3 2008
Issue 2 2008
Issue 1 2008
Industry Focus 2008
FAQs
Rainer Pepperkok
Yvonne Ibig-Rehm
Roderick L Beijersbergen
Peter O'Brien
GE Analytical Instruments
BD Biosciences
Perkin Elmer
Issue 3 2008
Biopharmaceutical
Peracetic acid in the study of rhIL-11 methionine oxidation
Toxicology
In vitro toxicity screening as pre-selection tool
About CIA
Paul French
Fred Wouters
Anthony Mitchell Davis
Syngene
Major Cancer Centre is using Dymension 2D Gel Analysis Software
US Research Centre uses 2D Gel Image Analysis Software
Rigaku
Parker Balston
Pall Life Sciences
Bruker Corporation
Bruker's New Advanced Supercon, Inc. (ASCI) Subsidiary Starts U.S. Operations and Hires Tom Rosa as CFO and Senior VP
Bruker Announces Breakthrough in Aerospace Metals Analytical Performance with the World’s First Handheld XRF to Include Silicon Drift Detector (SDD)
Bruker BioSpin 1.7mm MicroCryoProbe Wins R&D 100 Award for Delivering a Tenfold Jump in NMR Sensitivity for Small Sample Amounts
Bruker BioSpin’s MRI CryoProbe™ Selected for 2008 R&D 100 Award for Enabling Preclinical MRI on Mice at 60 Micrometer Spatial Resolution
Bruker AXS Microanalysis Introduces Ultra-fast EBSD System, Next-Generation 123 eV Resolution XFlash® Silicon Drift Detectors and New Particle Analysis Software
Hach Ultra
Carl Zeiss
Bruker Optics
Scientifica
Molecular Devices
Daniel Zicha
Marjo Simonen
Issue 4 2005
Issue 3 2005
Issue 2 2005
Issue 1 2005
Issue 1 2006
Issue 2 2006
Issue 3 2006
Article Reprints
Issue 4 2006
Online Marketing Opportunities
Issue 5 2006
Issue 6 2006
Industry Focus 2007
Issue 1 2007
Issue 2 2007
Issue 3 2007
Issue 4 2007
Issue 5 2007
Issue 6 2007
Industry Focus 2008
Issue 1 2008
Issue 2 2008
Industry News
Dr. Ravi Pawa appointed Medical Advisor at Synexus
Dr. Franz-Josef Kappenberg is new qualified person at HÄLSA Pharma
Lipoxen announces Board Changes
Hybrigenics appoints Eric Castaldi to its Board of Directors
CRF Inc. Strengthens Clinical Advisory Board
BT Pharma appoints Thierry Hercend as President of its Supervisory Board
Lipoxen Chief Scientific Officer, Professor Gregory Gregoriadis, Awarded Two Lifetime Achievement Honours
Protein Crystallisation
New opportunities for protein crystallisation
The current challenge
Procurement
More than just cost cutting
Project Management
Taking care of innovation
European Pharmacopoeia
Analysing the monographs
Microdosing
Tool for candidate drug selection
Drug Safety
In vitro safety pharmacology profiling
Electrophysiology
In vitro and in vivo techniques in CNS drug discovery
Clinical Development
Integration is key
Site Development
Investing in Bavarian biotechnology
Events
For Advertisers
For Authors
Contract Sales
Effective secondary care teams
Strategic Alliances
Partnering for better science
Lyophilization
An ever-evolving technology
The current state of PAT in freeze drying
Terahertz Spectroscopy
New opportunities for understanding
Vaccine Technology
Maintaining vaccine security
Cellular Imaging
Cell-based imaging
HTS
Science in Seattle
Launching an HTS campaign to discover new antivirals
HTS technologies to facilitate chemical genomics
Pursuing hot targets in drug discovery
The role of HTS in eADMET profiling
Affinity-based screening
Collaborating to find new approaches to tropical disease
Setting new standards in Ultra HTS
Efficient HTS in the nanoliter range
Integration of miniaturisation technologies
Ion Channel Drug Discovery
Bottlenecks and potential improvements
Critical success
A new approach to ion channel hit identification
The road ahead and how to get there
Patch clamp electrophysiology steps up a gear
Cell Culture Automation
Is the dream becoming reality?
Platform technology for routine three dimensional cell culture
Next Issue
Functional Genomics
Is Pharma getting what it needs from RNAi?
RNAi therapeutics for neurodegenerative disease: challenges and prospects
Size does matter: macro ncRNAs and the regulation of imprinted gene clusters - Issue 1/08
MicroRNAs and their relatives – new avenues in biomedical research
The expanding world of small RNA: from germ cells to cancer
In vivo drug target validation using RNAi
How will MicroRNAs affect the drug discovery landscape?
RNAi: an attractive choice for future therapeutics
Inducible systemic RNA silencing in Caenorhabditis elegans
Cancer immunotherapy using RNAi
Assessing the current proteomics field
Genomics for the new biomedicine
A new field in biomarker discovery and target identification
Challenges in High-Content siRNA Screening
The right approach to human therapy
A new approach to specify RNAi experiments
MitoCheck: checking mitosis
Czech out RNAi
Novel antisense drugs for micro-RNA therapeutics
HTS using siRNA libraries
Applications in target ID and validation
The promise and pitfalls
Target validation
Forging therapeutics from small interfering RNAs
RNAi therapeutics: addressing targets?
MicroRNAs for high-throughput functional analysis
Ion Chromatography
Advances in fast ion chromatography
Metabonomics
Evaluating drug safety
Technology Transfer
Ten steps to success
Tablet Compaction
Die-wall stress measurement
Rheology
The future of process design
Raman Spectroscopy
RS coupled to separations
Applications in bioprocesses and biotechnology
The rise of Raman
Exploring new sources of raw material
Receptor Binding
A powerful tool for drug discovery
Analytical Techniques
Pharmaceutical analysis in drug development
Pharmaceutical analysis in quality control
Outsourcing
Specialisation impacts the European Contract Research Services market
Contract Manufacturing Organisations poised for great opportunities
CROs as a strategic fit – the one stop shop for R&D services
Unlocking the potential of the Asian giants
An integral role for CROs
RFID Technology
A new challenge in the pharmaceutical supply chain
Microdialysis
Novel strategies for antidepressant drug discovery
Biomarkers
Biomarkers in neurodegenerative diseases
Designing a program for early CNS development
Biomarkers of efficacy and safety
The promise of pancreatic beta cells
Applications in drug development
Freeze Drying
Spray-freeze-drying in the manufacture of pharmaceuticals
PAT for freeze drying: cycle optimisation in the laboratory
Lyophilization: cycle robustness and process tolerances, transfer and scale up
Ion Channel Electrophysiology
Four years and counting for automation
Ion channel electrophysiology in pharmaceutical research
High throughput electrophysiology platforms as enablers
Clinical Trials
Roundtable: The future direction for clinical trials
Taking clinical trials into the future
Getting the balance right
Cell Line Optimisation
Maximising the efficiency and application of automated planar patch clamp electrophysiology
Protein Crystallography
Protein crystallography in drug design: current bottlenecks
Structural genomics, the practical way
Automated classification of crystallisation images
Streamlining with automation and robotics
Science through cooperation
Synchrotron radiation: current status and future landscape
Cleanrooms
Trends in pharmaceutical cleanroom technology
HVAC energy savings in the pharmaceutical industry
Maintaining a spore-free environment in the cleanroom
Cleanroom standards
Co-operation through certification
International standards: a tool for compliance
Microbiology
Microbiology/ Microbiologists – Where next?
Cutting edge technologies and their potential role in pharmaceutical microbiology
A “PAT” on the back for Rapid Microbiological Methods
The significance and detection of VBNC microorganisms
Are the needs of the pharmaceutical industry being met?
Polyphasic approach to microbial identification
The current market and future trends for RMM
Solutions for the next stage
Opportunities for Rapid Microbial Methods
Microbial detection in mammalian cell culture systems
Implementation, validation and registration
Implementation, validation and registration of rapid microbiological methods
Lab Automation
High throughput materials discovery “reducing product time to market”
Driving lab automation forward
The impact of automation on drug discovery
The state of industrial laboratory automation
Quo vadis, Laboratory Automation Education?
A roadmap for development
Merck & Co.’s automated compound distribution centre
The AstraZeneca ACMF
Show Previews
SBS: Enhancing Research Productivity
56th Annual ASMS Conference
Lab Automation 2008: Where science, technology and industry come together
ELRIG: Protein Crystallography
HET Instruments 2008: innovations products and services
1st European Conference on Process Analytics and Control Technology
Interpack 2008: Processes and packaging
ABRF 2008: enabling technologies in the life sciences
Analytica 2008: the communication and business event for the international community
Pittcon 2008: 59th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy
IFPAC: 22nd international forum for Process Analytical Technology
Pep Talk: The definitive protein focused event
Protein Crystallography meets Virtual Discovery
MicroRNAs: Biology to Development and Disease
RNAi Europe 2007: Roundup
Biotechnica
An international display of processing excellence
ICSE 2007, the International Contract Services Expo
RNAi Europe
The 6th Annual HUPO World Congress, Seoul 2007
First joint European Laboratory Robotics Interest Group and Society for Biomolecular Studies meeting
IBC’s 12th Annual World Congress Drug Discovery & Development of Innovative Therapeutics
Integrative proteomics: maximising the value of proteomics
Automated liquid handling
Pharmintech 2007
55th ASMS Conference on Mass Spectrometry
Landscaping pharmaceutical research
Advancing the science of drug discovery
Brain briefings
ABRF 2007: Creating the Biological Roadmap
21st International Forum Process Analytical Technology
Still talking about proteins
Where laboratory technologies emerge and merge
First of a kind in Cambridge
Translating proteomics from bench to bedside
World’s best in pharma manufacturing
Cherry picking in drug discovery
Integrating science, tools and technologies with systems biology
The expo for modern laboratory equipment
‘Living in interesting times’
Serving laboratories for two decades
The European innovation exchange for proteomics
The Protein Information Week
Recognising innovation and advances
Three events in one
Presenting the latest in drug discovery
Best practice strategies for manufacturing excellence
Proteomics: from technology to new biology
ADME and the Application of Laboratory Automation
FENS: Preview
RNAi Europe & Advances in qPCR
7th HUPO World Congress
HUPO 2008 – Proteome Biology
Drug Discovery 2008
Product News
PerkinElmer expands line of Gas Chromatography/Mass Spectrometers
Applied Biosystems/MDS Analytical Technologies introduces next generation mass spectrometry systems
Bruker to Host Webinar on Small Molecule Characterization with Complete Molecular Confidence on October 28
Bruker Introduces HyperQuant, a Unique Bench-Top NMR Reader to Quantify Hyperpolarization
Tecan’s Infinite M1000, Infinite F500 and Safire2 multimode readers are Transcreener Far Red FP validated by BellBrookLabs
New in vitro toxicology application for DRAQ5
Tecan offers outstanding service to US customers
FOSS NIRSystems introduces new vials
Applied Biosystems Introduces New Rapid Molecular-based System for Mycoplasma Contaminant Detection in Biopharmaceutical Manufacturing
New opportunities for live cell flow cytometry with CyTRAK Orange
REACTS Goes from Strength to Strength
TTP LabTech extends liquid handling capabilities for HTS
TTP LabTech helps TTP Group win the prestigious Queen’s Award for Enterprise in International Trade
PCR
The role of chemokines in type 1 diabetes: as assessed by RT-PCR
Night on Highway 128
Analysis of microRNA expression by qPCR
The real-time reverse transcription polymerase chain reaction – treat with caution
Real-time PCR gene expression profiling
Quantitative PCR assays in clinical drug development
Real-time PCR: clinical applications
Making the lab workhorse run faster
Gold standard
Real-time quantitative PCR – opportunities and pitfalls
Personalised Medicine
Personalised medicine: are we ready for the revolution?
HCS
High content screening as improved lead finding strategy
Genome-wide High Content Analysis of cellular pathways
Automated workflow optimisation and assay development strategies for High Content Research Facility, Trinity College Dublin
Statistical techniques for handling high content screening data
Identifying human toxicity potential
Academic contribution to high-content screening for functional and chemical genomics
The handling and analysis of large scale high content screening data
Neuronal morphology screening as a tool in neuroscience drug discovery
Achieving the potential of HCS
A perspective from Eli Lilly and Co.
Carving a niche in the realm of drug discovery
Connecting HCS to CNS drug targets
A bright future for drug discovery and development
Support for lead optimisation and target validation
Getting a handle on neuronal behaviour in culture
High content imaging subpopulation analysis for phenotypic drug discovery
Utilisation of secondary screening
Live cell high content screening in drug development
LIMS/ELNS
Going paperless: is now the time?
Implementation of an enterprise ELN: a case study
The right technology, at the right time
Interfacing LIMS with ELN
Information automation in R&D laboratories; past and future
Aseptic Processing
Test method validation for cleaning validation samples
Advanced Aseptic Processing: RABS and Isolator Operations
Thermal Analysis
Thermal analysis and calorimetry: latest developments
Enthalpic efficiency and the role of thermodynamic data in drug development: possibility or a pipeline dream!
A new era for microcalorimetry in drug development
Calorimetry for amorphous content quantification
Calorimetry for polymorph detection
Essential techniques for development
SCTA for pharma
Why is thermal analysis important to the industry?
Fast-scan differential scanning calorimetry
PAT
PAT: not a purpose in itself
PQLI – providing practical solutions
PAT: a comprehensive guide
The future direction of ASTM E55 Committee on manufacture of pharmaceutical products
An eight-step Six Sigma toll-gate approach to PAT implementation
The business benefits
Implementing Near Infrared Spectroscopy as a PAT tool in the biopharmaceutical industries
PAT in the pharmaceutical industry
PAT and design science
EuPAT: an initiative to promote progress in the science underpinning PAT
PAT and scalable automation for bioprocess control and monitoring
Pharmaceutical manufacturing – for now and the future
QbD and PAT – 2008 is the year it goes mainstream
PAT for the product lifecycle of a biopharmaceutical product
Committee E55 – an update
Wyeth forges ahead
The role of PAT in biotechnology
A vision for the future
Process analysis and control for profit
Cost, knowledge and convenience: facing the facts
Mass Spectrometry: another tool from the PAT toolbox
A Pfizer perspective
Harbinger of change
PAT – reducing the cost of quality in consumer products manufacturing
Wyeth’s PAT variations submitted through the EMEA Worksharing Procedure
Quality by Design, Validation, and PAT: operational, statistical, and engineering perspectives
Company A-Z
Proteomics
Antibody-based proteomics to study cellular signalling networks
Proteomics in the pharmaceutical industry: is the analytical challenge just too large?
Proteomics – the frontiers and beyond
Biomarker discovery and validation in clinical proteomics
Stathmin immobilisation on a chip using an oligo-cysteine tag
Mass spectrometry-based proteomics: trends in tools and strategies
The role of phospho-proteomics in drug discovery and development
HUPO drives the creation of protein test standards
An essential role for the Michael Barber Centre
A showcase project for EU research
Structure, function, interaction
The future of proteomics
The human plasma proteome: A biomarker pool too deep to explore?
Amassing the latest in MS
Identification and prevalidation of safety biomarkers
The HUPO Brain Proteome Project
Meeting the challenge with a new facility
Plasma protein biomarker discovery
Initiatives from Spain
Easy access for the scientific community
A network of innovation from Canada
MALDI FT-ICR MS platform for proteomics: Rationale for an offline approach and optimised implementation
Accessing stem cells via proteomics
Home
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Proteomics Classified Directories
Electrophysiology Classified Directories
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Testimonials
Interviews
INDUSTRY INSIGHT – IDBS: Integrated framework
ToPics – effective training at your door-step
Industry Insight: Applied Biosystems – the next generation of sequencing
Industry Insight: Biology and data capture in the life sciences industry
Industry Insight: United they stand
Industry Insight: The measure of success
Spin-outs come of age
Quality through collaboration
US universities unite
A co-ordinated approach to RNAi
Plugging the gap
Siemens: innovation, industry and implementation
Expo sets a new standard in PAT implementation
Industry Insight: An interview with Søren Morgenthaler Echwald
Industry Insight: Exceeding innovation excellence
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