• Facebook
  • Twitter
  • LinkedIn
  • Google +
  • RSS

Bruker - Articles and news items

Fully Automated Structure Verification of Organic Compounds by Combining High Resolution Accurate MS with NMR Data Analysis

Poster note: Fully automated structure verification of organic compounds by combining high resolution accurate MS with NMR data analysis

Whitepapers / 20 April 2016 / Bruker Daltonik GmbH

Here we describe a new approach which automates structure verification for (synthetic) chemists…

Application note: Enhancing reaction understanding with online NMR reaction monitoring – application to chemical route development

Application note: Enhancing reaction understanding with online NMR reaction monitoring – application to chemical route development

Whitepapers / 11 January 2016 / Anna L. Dunn, Analytical Research and Development, Pfizer, Department of Chemistry, University of Wisconsin / Anna Codina, Bruker UK Limited / David A. Foley and Mark T. Zell, Analytical Research and Development, Pfizer

In this work, we demonstrate the complementarity of NMR and infrared (IR) spectroscopy and show the use of NMR to improve the understanding and robustness of the synthesis of an active pharmaceutical ingredient (API) precursor…

MALDI High-Throughput Screening beyond 100,000 Samples per Day in Drug Discovery

Poster note: MALDI high-throughput screening beyond 100,000 samples per day in drug discovery

Whitepapers / 17 November 2015 / Bruker and Novartis

This work focuses on the improvement of MALDI-TOF automation parameters to further increase sample analysis speed in HTS assays to more than 100,000 samples per day…

Bruker app note September 2015

Application note: High-throughput Screening of Deubiquitylase enzyme (DUB) activity/specificity and inhibitor screening by MALDI-TOF mass spectrometry

Whitepapers / 1 September 2015 / Bruker Daltonik

In biopharmaceutical laboratories, there is a growing need for high-throughput, yet sensitive methodologies to characterize deubiquitylase enzymes (DUBs) and DUB inhibitors…

Bruker Opterra-II™

Bruker introduces Opterra II Multipoint Scanning Confocal Microscope

Supplier news / 11 August 2015 / Bruker

High-speed confocal system provides most quantitative and flexible live-cell imaging…

Bruker Webinar Feature

Accelerating Pharma R&D using Mass Spectrometry and NMR

Webinars / 14 May 2015 / Bruker Daltonics

In this recorded webinar three experts from Bruker Daltonics and University of Dundee introduce novel MS and NMR solutions and its applications in pharmaceutical research…


Bruker launches new BRAVO Handheld Raman Spectrometer for Raw Materials identification

Supplier news / 19 March 2015 / Bruker

Bruker announces the launch of the new BRAVO handheld Raman spectrometer for identification of raw materials…


Bruker Announces the New S2 PUMA Bench-top X-ray Fluorescence Spectrometer for Elemental Analysis

Supplier news / 19 March 2015 / Bruker

At Pittcon 2015, Bruker Announces the New S2 PUMATM Bench-top X-ray Fluorescence Spectrometer for Elemental Analysis…

Near infrared spectroscopy (NIR) Supplement

Near Infrared Spectroscopy: In-depth focus 2014

Issue 1 2014, Near-infrared spectroscopy, Supplements / 9 April 2014 / Otto Scheibelhofer, Stephan Sacher, Johannes G. Khinast, Matthieu Clavaud, Yves Roggo

Near infrared light spectroscopy: Applicability and new developments
Near infrared spectroscopy: in-line biopharmaceutical Chinese Hamster Ovary cell culture monitoring

Application Notes 2013 - Bruker

App Note: Bruker Optik – TANDEM FT-NIR for on-line tablet characterisation

Whitepapers / 16 December 2013 / Bruker Optik

Pharmaceutical manufacturers are required to enhance their critical quality performances. This is being encouraged by the FDA, which is pushing towards using modern process analytical technology (PAT) to ensure the quality of the final product. A large number of applications in the Process Analytical Technology (PAT/QbD) initiative can be addressed using FT-NIR spectroscopy. For drug product sites for instance, NIR spectroscopy can be used at almost every step of tablet manufacture from raw material control over granulation and drying to content uniformity analysis of the dosage unit…

Mass Spectrometry Supplement 2013

Mass Spectrometry: In-depth focus 2013

Chromatography, Issue 2 2013, Supplements / 17 April 2013 / Uwe Christians, Jelena Klawitter, Jost Klawitter, George McLeod, Min Yang

Corticosteroids and mass spectrometry; latest applications using LC/MS3.
Multi-analyte LC-MS/MS assays for the quantification of endogenous compounds during the development of drugs and companion diagnostics…

Near Infrared (NIR) In-deptch focus 2013

Near Infrared Spectroscopy: In-depth focus 2013

Issue 1 2013, Near-infrared spectroscopy, Supplements / 18 February 2013 / Pierre-François Chavez, Charlotte De Bleye, Pierre-Yves Sacré, Eric Rozet, Philippe Hubert, Eric Ziemons, Nicolas Abatzoglou, Eddy Castellanos Gil and Ryan Gosselin

Validation methodologies of near infrared spectroscopy methods in pharmaceutical applications.
Evaluating the influence of hopper geometry on radial and axial concentration profiles in flowing granular mixtures.


Webinar: Use of MicroNIR to optimise fluid bed drying and to reduce waste at tablet compressionFIND OUT MORE
+ +