Chloride channels - Articles and news items

Chloride ion channels and transporters

Chloride ion channels and transporters: from curiosities of nature and source of human disease to drug targets

Drug Targets, Issue 4 2013 / 20 August 2013 / Jonathan D. Lippiat, School of Biomedical Sciences, University of Leeds

Early in their undergraduate education, the student is introduced to various types of integral membrane protein: receptors, adhesion proteins, ion channels, ion pumps and ion transporters. As they progress through their studies, they find out that discrete gene families and protein structures are responsible for these different protein classes and there is never any reason to consider that there might be any ambiguity in assigning any particular protein to its appropriate protein class.

Drug Targets Supplement 2012

Drug Targets: In-depth focus 2012

Drug Targets, Issue 6 2012, Supplements / 11 December 2012 / Patricia McDonald / Emmanuel Sturchler / Dayue Darrel Duan

GPCR allosteric modulation: new opportunities and challenges for drug discovery.
Chloride channels and cardiac arrhythmia: novel therapeutic targets?


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