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Conor McSweeney - Articles and news items

Pills in Wrapper

PAT for packaging: review of applications for expeditious, nondestructive quality testing

Issue 2 2014, PAT & QbD / 15 April 2014 / Jose Montenegro-Alvarado, Bradley Diehl, Jean-Maxime Guay, Steve Hammond, Hiwot Isaac, Ben Lyons, Conor McSweeney, Seamus O’Neill, Jean-Sébastien Simard and Joep Timmermans, Pfizer Inc.

This article reviews some emerging applications of Process Analytical Technologies (PAT) for packaging quality testing. Specifically, four commercially-available packaging applications are explored in further detail: Raman spectroscopy for rapid material identification testing of polymeric packaging materials; vision-based elastic deformation for non-destructive blister integrity testing; X-ray monitoring for inline blister fill inspection; and thermal imaging for inline verification of bottle foil seal integrity. For each application, a brief review is provided stating technology capabilities and principles of measurement as well as sharing example(s), other relevant remarks covering some practical aspects and comments on considerations for building a business case for these technologies.

Raman Supplement 2012

Non-destructive material identification: In-depth focus 2012

Issue 5 2012, Raman Spectroscopy, Supplements / 24 October 2012 / European Pharmaceutical Review

An implementation perspective on handheld Raman spectrometers for the verification of material identity.
Portable Raman spectroscopy for pharmaceutical counterfeit detection.
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