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Louis Stancato

 

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High content imaging subpopulation analysis for phenotypic drug discovery

Phenotypic drug discovery (PDD) has come of age – again.…

19 June 2008 | By

Phenotypic drug discovery (PDD) has come of age – again. Using a microscope to observe a cell, one of the oldest techniques available to a cellular biologist dates back to the 17th century studies of Antony van Leeuwenhoek and his characterisation of ‘animalcules’. These early analyses, which simply described the…

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A perspective from Eli Lilly and Co.

Advances in optical imaging methods, personal computer power and cell/molecular…

23 May 2006 | By Aidas Kriauciunas and William Roell, Department of Integrative Biology, Shaoyou Chu, Karen Cox and Jonathan A. Lee, Department of Lead Generation Biology and Lead Optimization Biology, Ann Goodspeed, Discovery Informatics, Louis Stancato, Cancer Growth and Translational Genetics, Mark Uhlik, Tumor Microenvironment Biology, Lilly Research Laboratory, Eli Lilly and Company

Advances in optical imaging methods, personal computer power and cell/molecular biology methodology have merged to form the field of ‘Cellomics’1 also referred to as High Content Cellular Imaging (HCCI). HCCI is a powerful and flexible cell-based assay platform that has the potential to shorten cycle times by broadly impacting the…