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Stem Cells - Articles and news items

Stem cell nano drug delivery applications to treat diabetes

Stem cell nano drug delivery applications to treat diabetes

Drug Delivery, Issue 2 2016 / 4 May 2016 / Vishal Shahidadpury, Anjali Hirani and Yashwant Pathak - University of South Florida Health

Stem cell therapy is currently utilised in medicine for its application in tissue repair and regenerative medicine. Unique characteristics of stem cells, such as self-renewal and differentiation, allow its function to be applicable for therapeutic purposes. Nanotechnology and cell microencapsulation have been researched and used as a means to protect cells from innate immune responses while permitting targeted drug delivery, as well as for sustained release of therapeutic agents to specific organs or cells. This review will provide an overview of stem cells, the purpose of nanotechnology and various surface modifications of nanoparticles for enhanced drug delivery, as well as describe how stem cell therapy is used for type 1 and type 2 diabetes mellitus. Additionally, a specific application of nanoparticle encapsulation and human embryonic stem cells in achieving glycaemic control, as seen in type 1 diabetes-induced immune-competent mice, will be discussed…


First patient treated in trial of ReNeuron’s retinitis pigmentosa cell therapy

Industry news / 15 March 2016 / Victoria White

ReNeuron has demonstrated that its Human Retinal Progenitor Cells (hRPCs) improve visual acuity in preclinical models of retinal degeneration…


MS treatment, AHSCT, shows “remarkable” results

Industry news / 18 January 2016 / Victoria White

Autologous haematopoietic stem cell transplantation (AHSCT), developed at Sheffield Teaching Hospitals, has shown ‘remarkable’ results in patients with MS…

stem cell therapy

Stem cell therapy does not provide significant improvement in Crohn’s disease

Industry news / 17 December 2015 / Victoria White

A clinical trial to test the effectiveness of a stem cell therapy among adults with difficult to treat Crohn’s disease has found it is not significantly better than conventional treatment in producing sustained disease remission after one year…


Data from four trials support the safety and tolerability of hESC-derived retinal pigment epithelium

Industry news / 25 June 2015 /

Results of four trials provide additional evidence supporting the safety and tolerability of hESC-derived retinal pigment epithelium…


Trial of new stem cell therapy for dystrophic epidermolysis bullosa (RDEB) gives promising results

Industry news / 1 June 2015 /

Results from a trial of a new stem-cell based therapy for a rare skin condition, recessive dystrophic epidermolysis bullosa (RDEB), have been published…

Stem Cells Supplement

Stem Cells: In-depth focus 2015

Genomics, Issue 2 2015, Supplements / 20 April 2015 / Yu Wang, David Hay, Andreas Bender, Yasaman Kalantar Motamedi, Maryam Peymani, Mohammad Hossein

In this free-to-view stem cells in-depth focus, you can find out how computational (‘in silico’) methods can help to rationally choose bioactive small molecules to improve stem cell differentiation. The differentiation of pluripotent stem cells to hepatocyte-like cells is the focus of a second interesting article…


Ocata Therapeutics licenses induced pluripotent stem cell (iPSC) technology from Allele Biotechnology

Industry news / 24 March 2015 / Victoria White

Ocata has announced that it has entered into a definitive agreement with Allele to access Allele’s proprietary technology for generating human iPSCs…


Promethera Biosciences receives approval in Belgium to enroll patients in the imminent HEP002 Phase IIb/III clinical trial

Industry news / 15 October 2014 / Promethera Biosciences

HEP002 trial represents the world’s first Phase IIb/III trial with a stem cell-based medicinal product for the treatment of urea cycle disorders patients…

Harvard logo

From stem cells to billions of human insulin-producing cells

Industry news / 10 October 2014 / The Harvard Stem Cell Institute

Giant step toward new diabetes treatment…

Smart Cells

New study shows UK public are largely unaware of stem cells as the potential uses are still being realised

Industry news / 9 October 2014 / On Broadcast

18 years since the first cord blood transplants were performed in the UK, public knowledge on this life-saving process is still sorely lacking. A study of over 4,000 people found that nearly a third (32%) of Britons did not know you can store umbilical cord blood and tissue, while the vast majority (85%) agreed there is a lack of awareness…

Lonza L7

Stem cells: from bench to drug development

Supplier news / 6 August 2014 / Don Paul Kovarcik, Lonza Walkersville, Inc.

Working in stem cell research can be both immensely rewarding and notoriously difficult. Lonza’s Don Paul Kovarik discusses the challenge of translating new advances in stem cell biology into viable, impactful therapies for patients…


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