article

Learning from clinical microbiologists – culturomics and metagenomics

In recent years there has been significant interest in the sequencing of the human microbiome and what can be learned from this project. One particular area of interest is those normally occurring microorganisms in the human gut.

metagenomics

It is believed that the human gut microbiota is responsible for maintaining health as well as disease pathogenesis.The study of gut microbiota has necessitated the development of new culture and evaluation methods – Lagier, et alindicated that as many as ~80 percent of the human gut bacteria were unknown and considered “unculturable.” This term is similar to the one used by many pharmaceutical microbiologists – viable but not culturable (VBNC). To remedy this, clinical microbiologists started using new, non-conventional methods – a practice termed the “rebirth of culture in microbiology.”1

The rest of this content is restricted - login or subscribe free to access

European Pharmaceutical Review issue 1 2019 coverThank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.

Why subscribe? Join our growing community of thousands of industry professionals and gain access to:

  • bi-monthly issues in print and/or digital format
  • case studies, whitepapers, webinars and industry-leading content
  • breaking news and features
  • our extensive online archive of thousands of articles and years of past issues
  • ...And it's all free!

Click here to Subscribe today Login here

 

Send this to a friend