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Microfluidics in cell-to-cell signalling measurements

30 June 2016 | By ,

Hormones are secreted molecules that carry biological information between cells. This type of cell-to-cell communication is vital to human life, and its dysregulation often underlies disease. In fact, the largest known class of cell surface receptors involved in hormone communication, G-protein coupled receptors, are also the largest class of known…

PAT Series: Recent achievements in NIR-based on-line monitoring of lyophilisation processes

30 June 2016 | By Adrian Funke - Bayer Pharma AG / Reinhard Gross, Stephan Tosch and Albert Tulke - Bayer Technology GmbH

Process analytical technology (PAT), namely near-infrared (NIR) and Raman spectroscopy, has already been shown to be a useful tool for monitoring, analysing and optimising the complex process of lyophilisation. The latter process is especially challenging in the case of biopharmaceutical formulations due to the instability of active ingredients, leading to…

Antibiotics resistance Q&A

30 June 2016 | By

With the rise in drug-resistant bacterial infections heralding a new, dark era of medicine, antibiotics alternatives could one day become the first-line defence against infectious diseases. With the urgent need to find new approaches clear, Caroline Richards, Editor of European Pharmaceutical Review, interviewed Dr. Bjorn Herpers, Chief Medical Advisor of…

EU Referendum: Tell us what you think…

20 June 2016 | By Caroline Richards, Editor, European Pharmaceutical Review

With only days to go until Britain holds a referendum on its EU membership, we can't help but wonder how you feel...

Soligenix on IDR technology and SGX942

10 May 2016 | By Victoria White, Digital Content Producer

We discuss Innate Defense Regulator (IDR) technology with Soligenix's Chief Scientific Officer, Dr Oreola Donini, and find out more about SGX942...

AZP-531 and its potential in Prader-Willi Syndrome

9 May 2016 | By Victoria White, Digital Content Producer

In this exclusive interview, Thierry Abribat, president of Alizé Pharma, discusses AZP-531 and its potential as a treatment for Prader-Willi Syndrome...

CEIV Pharma: Industry cooperation that is taking off

4 May 2016 | By Ricardo Aitken and Michal Wielgus, IATA Consulting

Several air transport industry stakeholders and regulators have joined forces to create the Center of Excellence for Independent Validators in Pharmaceutical Logistics (CEIV Pharma) programme. This joint effort aims to effectively help reverse the current lack of standardisation, compliance and transparency currently afflicting the pharmaceutical air transport supply chain, via…

Inhibition of mutant P53 tumour cells by medicinal plants

4 May 2016 | By Osuntokun Oludare Temitope and Ogunleye Adewale Joseph, Adekunle Ajasin University

The aetiology of tumours is attributed to changes in many internal (molecular) factors, most of which include mutations in several regulatory mechanisms and the loss of cell differentiation. Human isoforms of the p53 protein play a key role in maintaining genetic stability, functioning as active tumour suppressors. However, a mutation…

New trends in intelligent robotics in the laboratory

4 May 2016 | By Dr. Patrick Courtney, tec-connection

While robotics systems have been useful tools in the laboratory for many years, most notably in the area of liquid handling, many tasks are still only automated to a small extent. At the same time a new wave of robotic devices is reaching the market – from robot lawn mowers…