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Avidity Biosciences

Novartis strengthens neuroscience pipeline with $12bn Avidity acquisition

27 October 2025 | By Catherine Eckford (European Pharmaceutical Review)

Deal to advance potential first-in-class RNA therapeutics focused on genetic neuromuscular diseases such as Duchenne muscular dystrophy.

article

Advancing AOCs to transform the delivery of RNA therapeutics

11 December 2023 | By Dr Michael Flanagan, Michael Flanagan

In this article, Dr Michael Flanagan discusses how a new class of medicines called antibody oligonucleotide conjugates (AOCs) have the potential to overcome a major challenge encountered with many established RNA-based therapeutics: delivery to tissues outside the liver. Last year, AOCs demonstrated the first-ever successful targeted delivery of RNA into…

news

First targeted delivery of siRNA into muscle

15 December 2022 | By Catherine Eckford (European Pharmaceutical Review)

A Phase I/II trial demonstrated the first successful targeted delivery of siRNA into muscle, using monoclonal antibody AOC 1001.

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Recommended

Avidity Biosciences

Novartis strengthens neuroscience pipeline with $12bn Avidity acquisition

Advancing AOCs to transform the delivery of RNA therapeutics

First targeted delivery of siRNA into muscle