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CAR-T

BCMA CAR T therapy facilitates potential autoimmune breakthrough

1 February 2024 | By Catherine Eckford (European Pharmaceutical Review)

First use of a BCMA CAR T-cell therapy for immune-mediated necrotising myopathy (IMNM), enabled sustained depletion of autoantibodies beyond 18 months, a study shows.

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Preventative approach could reduce immunotherapy side effects

4 January 2024 | By Catherine Eckford (European Pharmaceutical Review)

Research suggests that giving prophylactic treatment prior to immunotherapy could eliminate the need for the latter to be administered in hospitals.

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First RNA CAR-T therapy autoimmunity trial shows potential

23 June 2023 | By Catherine Eckford (European Pharmaceutical Review)

A novel RNA CAR-T cell therapy demonstrated long-term clinical benefit for most generalised myasthenia gravis (gMG) patients in a landmark study.

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Gut microbiome linked to cancer CAR T therapy response

13 March 2023 | By Catherine Eckford (European Pharmaceutical Review)

For patients with B cell lymphomas, the gut microbiome may modulate the efficacy of CAR-T immunotherapy, research has found.

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First successful CAR-T treatment for muscle inflammation

24 February 2023 | By Catherine Eckford (European Pharmaceutical Review)

Researchers in Germany have helped a patient to overcome anti-synthetase syndrome muscle inflammation using CAR-T cells.

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Global 2-year trial reports on CAR-T therapy to treat DLBCL

3 December 2018 | By European Pharmaceutical Review

A study has reported results of a clinical trial using CAR-T therapy where over half of the cancer patients were alive two years after the start...

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Cell therapy rejected for aggressive adult lymphoma on the NHS

24 September 2018 | By Iqra Farooq (European Pharmaceutical Review)

A CAR-T immunotherapy for adults with an aggressive form of non-Hodgkin lymphoma has been provisionally rejected by the NHS...

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NHS announces groundbreaking personalised child cancer treatment

5 September 2018 | By Iqra Farooq (European Pharmaceutical Review)

The NHS has announced a groundbreaking new treatment, CAR-T, for children with leukaemia...

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