bioBoaVista showcases its viral transport medium, that can stabilise samples, for efficient nasal tests for the diagnosis of COVID-19.
bioBoaVista, a Brazilian specialist culture media manufacturer for microbiological diagnosis, has developed a viral transport medium (MTV) for more efficient nasal tests for the diagnosis of COVID-19. The novel medium stabilises samples for significantly longer; up to 48 hours at room temperature and up to 5 days between 2°C to 8°C, compared to standard saline samples that last only 12 hours.
This report addresses the key factors shaping pharmaceutical formulation, including regulation, QC and analysis.
Access the full report now to discover the techniques, tools and innovations that are transforming pharmaceutical formulation, and learn how to position your organisation for long-term success.
What you’ll discover:
Key trends shaping the pharmaceutical formulation sector
Innovations leading progress in pharmaceutical formulation and how senior professionals can harness their benefits
Considerations and best practices when utilising QbD during formulation of oral solid dosage forms
Can’t attend live? No worries – register to receive the recording post-event.
The MTV is prepared with a cell culture medium, supplemented with proteins for viral stabilisation and the addition of antibiotics and antifungals to inhibit the growth of other microorganisms present in the nasal mucosa and the throat. This exclusive formulation prevents any interference in the stability of the virus through competition and contamination by other existing pathogens. Samples are collected using flexible plastic swabs that break inside the tube of transport, avoiding splashes and potential contamination. This process protects the quality of the sample for a longer period than traditional means, enabling more efficient transport and processing.
bioBoaVista’s diagnostic test is registered with ANVISA, the Brazilian Health Regulatory Agency. Using entirely local production means it does not depend on imports, which is of particular importance with current limited global transport.
The Company needed to efficiently fill its tubes up to the required 3ml level. bioBoaVista chose the Flexicon PF7 bench top filling machine from Watson-Marlow Fluid Technology Group (WMFTG) for its low shear, gentle pumping action. This ensures the valuable viral transport medium is transferred undamaged with high accuracy and precision.
With current batch sizes of two million units, the Company plans to increase its production to four times this and as such has scaled out capacity with additional PF7 machines. By choosing Flexicon, the Company also has the option to scale up further whilst retaining confidence in the technology. The FF30 is available to semi-automate the filling and capping process.
Precise, aseptic filling
bioBoaVista required a compact, efficient filling mechanism to fill its specialist media to the required level into the diagnostic test tubes. With precision filling from as low as 0.2ml and repeatable filling accuracies of better than 0.5 percent, the PF7 enables bioBoaVista to accurately and efficiently fill its tubes to the required level without costly overfilling.
Flexicon products are the preferred choice for the biotechnology and diagnostic industries, providing the required aseptic guarantees necessary for contamination free processes. The PF7 is the result of 30 years of industry-focused experience and comes with a five-year warranty as well as IQ/OQ documentation available on request to assist with process validation. It is designed to work with single-use fluid paths and connects to a range of balances and printers for error-free calibration to help compliance with GMP and regulatory demands.
Simple to operate
The PF7 is simple to operate, with a powerful user interface to reduce the risk of errors. Its clear and intuitive colour display and large keypad facilitate ease of use when
gowned up in cleanroom environments. This enabled bioBoaVista to fill its tubes whilst maintaining sterility to meet regulatory requirements.
Scale-out to scale-up
The global challenge of the COVID-19 pandemic requires widespread testing to diagnose those with the virus and to limit the spread. The availability of reliable tests is therefore essential, and organisations worldwide have been developing tests and expanding their production to meet this need. bioBoaVista’s test media maintains sample stability for significantly longer, allowing samples to be taken in isolated areas and shipped back to testing facilities without degradation or contamination.
In order to rapidly scale-up the number of tests the Company produces, it has increased its PF7 filling capacity to seven machines that will run in parallel. This trend towards increasing capacity by scaling-out identical production lines is becoming more common with the growth of affordable, single-use technologies, a valuable development that enables rapid scale-up when time is scarce.
The Flexicon PF7 has ensured that bioBoaVista can efficiently fill its viral transport media to precise volumes whilst maintaining sterility. Its reliability and ease of use has led the Company to significantly expand its production capabilities with additional machines that will increase the number of testing kits produced by four times and facilitate essential widespread testing.
This website uses cookies to enable, optimise and analyse site operations, as well as to provide personalised content and allow you to connect to social media. By clicking "I agree" you consent to the use of cookies for non-essential functions and the related processing of personal data. You can adjust your cookie and associated data processing preferences at any time via our "Cookie Settings". Please view our Cookie Policy to learn more about the use of cookies on our website.
This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorised as ”Necessary” are stored on your browser as they are as essential for the working of basic functionalities of the website. For our other types of cookies “Advertising & Targeting”, “Analytics” and “Performance”, these help us analyse and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these different types of cookies. But opting out of some of these cookies may have an effect on your browsing experience. You can adjust the available sliders to ‘Enabled’ or ‘Disabled’, then click ‘Save and Accept’. View our Cookie Policy page.
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Cookie
Description
cookielawinfo-checkbox-advertising-targeting
The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertising & Targeting".
cookielawinfo-checkbox-analytics
This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Analytics".
cookielawinfo-checkbox-necessary
This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-performance
This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Performance".
PHPSESSID
This cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website. The cookie is a session cookies and is deleted when all the browser windows are closed.
viewed_cookie_policy
The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
zmember_logged
This session cookie is served by our membership/subscription system and controls whether you are able to see content which is only available to logged in users.
Performance cookies are includes cookies that deliver enhanced functionalities of the website, such as caching. These cookies do not store any personal information.
Cookie
Description
cf_ob_info
This cookie is set by Cloudflare content delivery network and, in conjunction with the cookie 'cf_use_ob', is used to determine whether it should continue serving “Always Online” until the cookie expires.
cf_use_ob
This cookie is set by Cloudflare content delivery network and is used to determine whether it should continue serving “Always Online” until the cookie expires.
free_subscription_only
This session cookie is served by our membership/subscription system and controls which types of content you are able to access.
ls_smartpush
This cookie is set by Litespeed Server and allows the server to store settings to help improve performance of the site.
one_signal_sdk_db
This cookie is set by OneSignal push notifications and is used for storing user preferences in connection with their notification permission status.
YSC
This cookie is set by Youtube and is used to track the views of embedded videos.
Analytics cookies collect information about your use of the content, and in combination with previously collected information, are used to measure, understand, and report on your usage of this website.
Cookie
Description
bcookie
This cookie is set by LinkedIn. The purpose of the cookie is to enable LinkedIn functionalities on the page.
GPS
This cookie is set by YouTube and registers a unique ID for tracking users based on their geographical location
lang
This cookie is set by LinkedIn and is used to store the language preferences of a user to serve up content in that stored language the next time user visit the website.
lidc
This cookie is set by LinkedIn and used for routing.
lissc
This cookie is set by LinkedIn share Buttons and ad tags.
vuid
We embed videos from our official Vimeo channel. When you press play, Vimeo will drop third party cookies to enable the video to play and to see how long a viewer has watched the video. This cookie does not track individuals.
wow.anonymousId
This cookie is set by Spotler and tracks an anonymous visitor ID.
wow.schedule
This cookie is set by Spotler and enables it to track the Load Balance Session Queue.
wow.session
This cookie is set by Spotler to track the Internet Information Services (IIS) session state.
wow.utmvalues
This cookie is set by Spotler and stores the UTM values for the session. UTM values are specific text strings that are appended to URLs that allow Communigator to track the URLs and the UTM values when they get clicked on.
_ga
This cookie is set by Google Analytics and is used to calculate visitor, session, campaign data and keep track of site usage for the site's analytics report. It stores information anonymously and assign a randomly generated number to identify unique visitors.
_gat
This cookies is set by Google Universal Analytics to throttle the request rate to limit the collection of data on high traffic sites.
_gid
This cookie is set by Google Analytics and is used to store information of how visitors use a website and helps in creating an analytics report of how the website is doing. The data collected including the number visitors, the source where they have come from, and the pages visited in an anonymous form.
Advertising and targeting cookies help us provide our visitors with relevant ads and marketing campaigns.
Cookie
Description
advanced_ads_browser_width
This cookie is set by Advanced Ads and measures the browser width.
advanced_ads_page_impressions
This cookie is set by Advanced Ads and measures the number of previous page impressions.
advanced_ads_pro_server_info
This cookie is set by Advanced Ads and sets geo-location, user role and user capabilities. It is used by cache busting in Advanced Ads Pro when the appropriate visitor conditions are used.
advanced_ads_pro_visitor_referrer
This cookie is set by Advanced Ads and sets the referrer URL.
bscookie
This cookie is a browser ID cookie set by LinkedIn share Buttons and ad tags.
IDE
This cookie is set by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. This is used to present users with ads that are relevant to them according to the user profile.
li_sugr
This cookie is set by LinkedIn and is used for tracking.
UserMatchHistory
This cookie is set by Linkedin and is used to track visitors on multiple websites, in order to present relevant advertisement based on the visitor's preferences.
VISITOR_INFO1_LIVE
This cookie is set by YouTube. Used to track the information of the embedded YouTube videos on a website.