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Pitt School of Medicine



Depression symptoms in remission after correcting metabolic deficiencies

12 August 2016 | By Niamh Louise Marriott, Digital Content Producer

Searching for answers through a series of biochemical tests, the scientists discovered that the patient had a cerebrospinal fluid deficiency in biopterin, a protein involved in the synthesis of several brain signalling chemicals called neurotransmitters. After receiving an analogue of biopterin to correct the deficiency, the patient's depression symptoms largely…