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Andrew Middleton

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The increasing use of Microbial Genotypic Techniques for the Identification of Pharmaceutical Isolates

The historical demarcation of prokaryotes has not been by way…

10 January 2009 | By

The historical demarcation of prokaryotes has not been by way of a specific scientific-based concept, but has been defined by a more arbitrary, anthropocentric system, rooted in the practical necessity of the time of its inception, based on the infor­mation available at the time. Therefore, species are historically defined on…

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Cutting edge technologies and their potential role in pharmaceutical microbiology

In order to meet the challenges demanded by the requirements…

23 November 2007 | By

In order to meet the challenges demanded by the requirements of Process Analytical Technology (PAT), the modern microbiological laboratory needs to become more innovative in microbial detection, identification and enumeration. Technology is becoming available that will speed up microbiological analysis, potentially allowing pharmaceutical microbiology tests to get as close as…

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Are the needs of the pharmaceutical industry being met?

Subsequent to the publication of the PDA technical Report Number…

25 January 2007 | By Dr Andrew M. Middleton, GlaxoSmithKline

Subsequent to the publication of the PDA technical Report Number 33 in 20001 there has been a multitude of articles published in pharmaceutical reviews and commentaries with regard to rapid microbial methods (RMM). The majority of these articles cover, to a greater or lesser degree, the technologies available and summaries…