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Royston Goodacre

 

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Application of deep UV resonance raman spectroscopy to bioprocessing

In recent years, Raman spectroscopy has been successfully applied to…

20 June 2011 | By Lorna Ashton and Royston Goodacre, School of Chemistry, Manchester Interdisciplinary Biocentre, University of Manchester

In recent years, Raman spectroscopy has been successfully applied to bioprocessing, including industrial processes. Raman studies have typically been aimed at measuring accurately both product yields and the presence of secondary products; including glucose and ethanol levels as well as secondary metabolites present in complex non-fractionated fermentation broths1,2. However, Raman…

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Raman spectroscopic techniques for biotechnology and bioprocessing

Biotechnological expertise is becoming increasingly important within the pharmaceutical industry,…

7 February 2009 | By

Biotechnological expertise is becoming increasingly important within the pharmaceutical industry, and will play a pivotal role in the monitoring of fermentations, particularly their optimisation within the framework of Process Analytical Technologies (PAT). The ability to harness biological processes for the development of drug therapies, so called ‘biopharmaceuticals’ provides treatments that…

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Applications in bioprocesses and biotechnology

Raman spectroscopy is a highly versatile tool that provides chemical…

11 November 2005 | By ,

Raman spectroscopy is a highly versatile tool that provides chemical fingerprints from biological material that can be interpreted using chemometrics and machine learning. In combination this powerful approach is being developed for the quantitative determination of multiple determinands in bioprocesses and for the characterisation of microorganisms.