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Vasculitis treatment market to expand in value to $558m by 2024

8 January 2016  •  Author: Victoria White

The vasculitis treatment market in the US, France, Germany, Italy, Spain, and the UK is expected to expand in value over the next decade, from under $342 million in 2014 to over $558 million by 2024,according to research and consulting firm GlobalData.

vasculitis treatment

The company’s latest report, OpportunityAnalyzer: Vasculitis – Opportunity Analysis and Forecast to 2024, states that the leading driver of this reasonably robust growth will be the anticipated launches of five biologics for the treatment of various forms of vasculitis, including Bristol-Myers Squibb’s (BMS) Orencia, Johnson & Johnson’s Remicade, GlaxoSmithKline’s (GSK) Benlysta and Nucala, and Roche’s Actemra.

Alexandra Annis, MS, GlobalData’s Analyst covering Immunology, says: “The regulatory approval of these drugs throughout the forecast period will introduce four novel mechanisms of action (MOAs) to the market, which will address current unmet needs well.

“The greatest unmet needs in the vasculitis market are improved safety and efficacy for both induction and maintenance therapies, as induction regimens for the management of vasculitis typically come with a considerable list of side effects.”

Actemra, Orencia and Nucala to be most successful new vasculitis treatment entrants

GlobalData believes the improved effectiveness and lack of inconvenient side effects that come with the introduction of these new MOAs offer exciting prospects for drug companies.

Annis explains: “The approval of biologics has the potential to result in big profits for pharma, as the cost of using them to treat a patient with vasculitis surpasses $16,000 per year. For this reason, vasculitis is an attractive area for label expansions.”

The analyst adds that Roche’s Actemra, BMS’s Orencia and GSK’s Nucala are anticipated to be the most successful of the new vasculitis treatment market entrants, as they have demonstrated strong efficacy and safety in clinical trials. Despite this, there will be barriers preventing the vasculitis market from reaching its full growth potential during the forecast period.

Annis continues: “The high cost of biologics will limit their uptake, especially in cost-conscious markets that are facing austerity measures. Cheaper biosimilars will challenge established brands.

“In addition, there will be challenges in gaining reimbursement of biologics approved as induction therapies for use as maintenance therapies, such as Rituxan.”

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