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Featured news, News / 3 August 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:SIAL), today announced a major breakthrough in the development of its proprietary CompoZr zinc finger nuclease (ZFN) technology with the release of more Knockout ZFNs covering the entire genomes of both mice and rats while reducing by half the pricing of products within the CompoZr ZFN portfolio. A new dedicated high-throughput manufacturing center, together with advances in ZFN design algorithms and production processes, has led to cost reductions in the development and production for both CompoZr Custom and Knockout ZFNs. This has allowed Sigma Life Science to extend the range of its Knockout ZFNs and to make ZFN technology more affordable to the scientific community. For more information visit www.sigma.com/zfn.
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Featured news, News / 22 July 2011 / kdm communications ltd
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq: SIAL), today announced the expansion of its CompoZr® Oncology Disease Model portfolio with the release of the first in its collection of breast cancer-specific knockout and knockin cell lines for drug discovery and research. These modified epithelial cell lines are expected to provide researchers with a characterized and known genetic background for basic research and pathway analysis. They are supplied with isogenic parental cell lines to allow high throughput, cell-based screening for drug discovery, target validation and mechanistic studies. For more information visit www.sigma.com/breastcancercells.
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Featured news, News / 5 May 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:SIAL), and King’s College London, today announced an exclusive license to develop and commercialize new technology for the identification and validation of microRNA (miRNA) targets in research and clinical diagnostics. For more detailed information, visit www.wherebiobegins.com/targetid.
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Featured news, News / 12 April 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:SIAL), today announced the signing of an agreement with Kraig Biocraft Laboratories, Inc. (KBLB) to develop genetically modified silkworms for the production of spider silk, using Sigma’s proprietary CompoZr Zinc Finger Nuclease (ZFN) technology. The transfer of silk genes from the spider to the silkworm is expected to allow the mass production of silk with enhanced strength and elasticity with potential textiles and biomedical applications, such as sutures, tendon and ligament repair, bulletproof vests, and automobile airbags.
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Industry news, News / 17 March 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:SIAL), have announced that its SAGE Labs initiative has created a suite of knockout rat models of Parkinson’s disease in collaboration with The Michael J. Fox Foundation for Parkinson’s Research (MJFF). Developed using the proprietary SAGEspeed™ model creation process, these off-the-shelf rat models represent a breakthrough in Parkinson’s disease research, overcoming the inherent limitations of the existing mouse models. For more information, on these animal models visit http://www.sageresearchmodels.com
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Featured news, News / 10 March 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich® (NASDAQ:SIAL), has announced the addition of 1,400 new European Collection of Cell Culture (ECACC) cell lines to its collection of cell line cultures and services. These cell lines have been fully authenticated and tested free of mycoplasma and can now be delivered within days to customers in the U.S., Mexico and Canada. ECACC is a recognized worldwide expert in the maintenance, cultivation and distribution of authenticated cell lines. The collection of cell lines can be accessed at www.sigma.com/ecacc.
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Featured news, News / 24 February 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:SIAL), today announced the release of its pre-designed CompoZr Knockout Zinc Finger Nucleases (ZFNs) technology to knockout any gene in the human genome. The new offer, attractively priced to fit within the budget of a typical laboratory, can generate permanent and heritable gene knockouts in human cell lines within weeks. For more detailed information, visit www.wherebiobegins.com/knockout.
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Featured news, News / 21 February 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:SIAL), today announced the addition of new genetically modified cancer cells to the Company’s range of high-quality cell lines. These human knockout and knock-in oncology cell lines, created using Sigma’s proprietary CompoZr® Zinc Finger Nuclease (ZFN) technology which received a silver medal as a Top Ten Innovations of 2010 from The Scientist magazine, offer researchers cellular models of cancer that are expected to enhance development of drugs for personalized medicine.
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Featured news, News / 17 February 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq: SIAL), today announced the release of OligoArchitect™, an online primer and probe design tool. This freely available tool offers automated design of probes and primers for real-time qPCR assays, powered by the industry standard Beacon Designer™ platform from PREMIER Biosoft, it complements Sigma Life Science’s comprehensive portfolio of oligonucleotide and qPCR products and customized oligonucleotide services. To access the OligoArchitect tool, visit wherebiobegins.com/probedesignonline.
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Featured news, News / 2 February 2011 / kdm communications limited
Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich® (Nasdaq: SIAL), today announced that its SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyze sequence data using next generation sequencing systems, while SAGE Labs plans to provide the samples and to host a new, free public database at sageresearchmodels.com in late 2011. The database will include exclusive genomic information and analysis tools.
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Featured news, News / 13 December 2010 / Sigma Life Science
Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich® (Nasdaq:SIAL), today announced that its SAGE Labs initiative has successfully used its proprietary CompoZr® Zinc Finger Nuclease (ZFN) technology to generate knock-in rats in which foreign genes have been inserted, or ‘knocked-in’, into the rat genome in a precisely targeted manner. This breakthrough achievement represents a major step forward in the creation of a transgenic animal, which may serve as more predictive models of human disease.
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Featured news, News / 22 November 2010 / kdm communications limited
Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich® (Nasdaq:SIAL), today announced the introduction of 1,700 new products to its collection of highly characterized Prestige Antibodies.
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