Thomas De Beer - Articles and news items

Raman Spectroscopy: In-depth focus 2014

Issue 1 2014, Raman Spectroscopy, Supplements / 10 April 2014 / Sara J. Fraser, Keith C. Gordon, Sigrid Pieters, Yvan Vander Heyden, Thomas De Beer

Raman spectroscopy in the study of pharmaceuticals: the problems and solutions to sub-sampling and data analysis
Conformational state analysis of proteins by Raman spectroscopy: univariate and multivariate methods
Raman Roundtable

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Raman spectroscopy for the analysis of drug products and drug manufacturing processes

Issue 2 2010, Raman Spectroscopy / 9 May 2010 / Prof. Thomas De Beer, Assistant-Professor, Process Analytical Technology, Faculty of Pharmaceutical Sciences, University of Ghent

This article aims at supplying a concise overview on the application of Raman spectroscopic analysis methods within the pharmaceutical drug product manufacturing world. Firstly, there will be a focus on the rapid and nondestructive off-line analysis feasibility of Raman spectroscopy for final drug products. Herewith, several possible sources of error will be discussed. Secondly, the applicability of Raman spectroscopy for in-process monitoring of drug product production processes will be highlighted. In addition, the tendency within the pharmaceutical industry to move from batch processing towards continuous manufacturing will be envisaged.


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