Scottish Medicines Consortium approves Kymriah® CAR-T therapy
The Kymriah (tisagenlecleucel) treatment has received a positive appraisal from the Scottish Medicines Consortium, after EMA approval last year.
The Scottish Medicines Consortium (SMC) has granted a positive appraisal to Kymriah® (tisagenlecleucel), a chimeric antigen receptor T-cell (CAR-T) therapy. The treatment is indicated for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who did not respond to two or more previous systemic treatments.
The decision was based on the results for the ongoing multi-centre, global registration JULIET clinical trial. It will be the first CAR-T therapy fully reimbursed for eligible UK patients on the UK National Health Service (NHS).
The CAR-T therapy uses each individual patient’s cells for their cancer treatment. T cells are drawn from the patient’s blood and reprogrammed in the laboratory to create T cells that are genetically coded to recognise and fight the tumour cells in the patient.
It will be the first CAR-T therapy fully reimbursed for eligible UK patients on the UK National Health Service (NHS)”
“Just over a year ago, CAR-T therapy wasn’t available in the UK or anywhere in Europe. Today’s positive appraisal by the Scottish Medicines Consortium represents a milestone as now all eligible patients across the UK can access Kymriah on the NHS regardless of indication or geography,” said Mari Scheiffele, Novartis Oncology General Manager, UK & Ireland.