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The role of water activity in the microbial stability of non-sterile pharmaceutical drug products

Aqueous, multiple-use, non-sterile drug products are susceptible to microbial contamination…

10 March 2015 | By

Aqueous, multiple-use, non-sterile drug products are susceptible to microbial contamination during their shelf life. To protect these products from this potential hazard to patients, they are formulated with antimicrobial preservatives. Other product attributes employed using the hurdle concept to prevent microbial contamination include: low pH, low redox potential, reduced storage…

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Microbiology: Mould contamination in pharmaceutical drug products and medical devices

Invasive fungal infections associated with high mortality rates are common…

15 December 2013 | By

Invasive fungal infections associated with high mortality rates are common in hospital settings, especially in intensive care units where patients may be immune-compromised, subject to invasive procedures and treated aggressively with antibiotics. The most common nosocomial fungal infections in descending order are due to the genera Candida, Aspergillus, Rhizopus, Fusarium…

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The current market and future trends for RMM

Following on from our latest report in Issue 4 in…

28 September 2006 | By Tony Cundell, Director, Pharmaceutical Sciences – Microbiology, Schering Plough Research Institute

Following on from our latest report in Issue 4 in which we outlined independent views on ‘solutions for the next stage’ in Rapid Microbiological Methods (RMM) from some of the industry’s leading names, Tony Cundell follows up with his own thoughts on this exciting field.