reference

Lankers M, Valet O, Laskina O. Subvisible particle identification in protein-based formulations by Raman spectroscopy. European Pharmaceutical Review. 2017;3:22-24

References

  1. Strehl, R, Rombach-Riegraf V, Diez M, Egodage K, Blueme, M, Jeschke M, Koulov A. Discrimination between silicone oil droplets and protein aggregates in biopharmaceuticals: a novel multiparametric image filter for sub-visible particles in microflow imaging analysis. Pharmaceutical Research. 2012;29(2):594-602.
  2. Siska C, Pierini C, Lau H, Latypov R, Fesinmeyer R, Litowski J. Free Fatty Acid Particles in protein formulations, part 2: contribution of polysorbate raw material. Journal of Pharmaceutical Science. 2015;104(2):447-456.
  3. Li J, Pinnamaneni S, Quan Y, Jaiswal A, Andersson F, Zhang X. Mechanistic understanding of protein-silicone oil interactions. Pharmaceutical Research. 2012; 29(6):1689-1697.
  4. Gerhardt A, Mcgraw N, Schwartz D, Bee J, Carpenter J, Randolph T. Protein aggregation and particle formation in prefilled glass syringes. Journal of Pharmaceutical Science. 2014;103(6);1601-1612.
  5. Jones, L, Kaufmann A, Middaugh C. Silicone oil induced aggregation of proteins. Journal of Pharmaceutical Science. 2005;94(4);918-927.

Send this to a friend