Roche and Nurix to advance potential best-in-class BTK degrader bexobrutideg

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Collaboration agreement expands Roche’s oncology pipeline and offers therapeutic potential across immunology and neurology.

Roche is licensing Nurix Therapeutics’ bexobrutideg (NX-5948), a Bruton’s tyrosine kinase (BTK) degrader with best-in-class potential, through deal worth up to $2.3 billion.

The co-development and co-commercialisation agreement is set to advance clinical development targeting B-cell malignancies, with wider potential across immunology and neurology.

In immunology, this includes chronic spontaneous urticaria and multiple sclerosis in neurology.

Nurix will receive…

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