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Epigenetic qPCR tool detects disease in newborns
The alternative method uses epigenetic quantitative real-time PCR (qPCR) assays and successfully detects a larger number of PIDs...
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Tecan’s Spark® reader aiding research into rare skin disease
Researchers at the University Hospital of Salzburg's EB House Austria are using a Tecan Spark® multimode reader to investigate epidermolysis bullosa (EB), a rare inherited disease that causes the skin to become ‘as fragile as a butterfly’s wings’, blistering in response to friction or trauma...
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Product Hub: Introducing ENDOZYME® II GO, endotoxin testing made faster, easier and more consistent
The rapid ENDOZYME® II GO assay is the latest member of bioMérieux’s ENDONEXT™ range of endotoxin detection assays based on sustainable recombinant horseshoe crab Factor C (rFC). The new assay caters to two important needs: efficiency and consistency...
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bioMérieux launches ENDOZYME® II GO, an innovative test for the detection of endotoxins in pharmaceutical microbiology control
bioMérieux, a world leader in the field of industrial microbiological control, announces the launch of ENDOZYME® II GO, a new endotoxin test in the bioMérieux ENDONEXT™ range of recombinant horseshoe crab Factor C (rFC) assays.
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Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumour tissue
Researchers have developed a highly specific apoptosis assay designed for immunofluorescence microscopy analysis of fixed core needle biopsy specimens...
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Sensitive new assay detects hepatitis B infection in single liver cells and serum
Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients...
article
Specificity in the recombinant factor C test for endotoxin
Limulus amebocyte lysate (LAL) users, compendial experts and regulators are still orienting themselves to the recombinant factor C (rFC) assay. Changes to compendial standards do not occur overnight and, for now, users willing to change must perform the alternative validation procedure USP .
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The future of cell culture: A new continuous bioprocess developed
A technique which allows the continuous production and collection of a cell has been developed removing the limit on the number of cells that can be grown in a culture dish...
article
Aqueous solubility-enhancing excipient technologies: a review of recent developments
At least some degree of solubility in water is necessary for active ingredients in pharmaceutical products to be effective in vivo. However, as efforts to discover and synthesise new active ingredients are pursued by industrial and academic medicinal chemists, achieving sufficient aqueous solubility can often be a significant limitation to…
whitepaper
Whitepaper: Sensitive and flexible bacterial endotoxin testing with the EndoZyme® II Recombinant Factor C Assay using the Synergy™ HTX Microplate Reader
This article covers how the EndoZyme II assay is established, optimised and validated using the SynergyTM HTX Multi-Mode Microplate Reader with Gen5TM software...
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Tecan offers walkaway automation for biochemical assays
Tecan’s innovative Spark® multimode reader can now provide walkaway processing of up to 50 assay plates per run with the addition of the new Spark-Stack™ integrated microplate stacker...
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Study predicts 1.2 million people in UK will be living with dementia by 2040
By 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), due to increased life expectancy...
editorial-board
Sheraz Gul
22 June 2017 | By
Head of Drug Discovery at the Fraunhofer Institute for Molecular Biology and Applied Ecology
article
Risk, benefit or cost: What stops patients from receiving a diagnostic test?
Diagnostic tests can help identify disease and disease probability in patients, leading to earlier treatment, but what’s the real cost?
news
Hands-on lateral flow test development workshop
6 June 2017 | By BBI Solutions
BBI Solutions, in partnership with Merck and Kinematic Automation, is hosting a lateral flow seminar designed to provide a practical insight into lateral flow test development...
