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‘Perfect’ polymer pill proves it can deliver
The crystal structure was found to have a half-life of 24 hours and could last in the bloodstream for more than 96 hours...
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Drug Delivery Systems
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Protein kinase C-alpha inhibitor reverses destructive nephritis
Inhibiting protein kinase C-alpha was shown to be a pivotal step towards restoring the damage done by nephritis...
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‘Nano-submarines’ to help target headaches and tumours
Tiny drug-filled nanocarriers, termed ‘nano-submarines’, are being developed to boost the targeted treatment of headaches and tumours, without damaging healthy tissue...
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Overcoming unusual challenges in the characterisation of a monoclonal antibodies by LC-MS from early to late stage of development
2 July 2018 | By SCIEX
Different modalities of monoclonal antibodies are pushing the limits of characterization by MS: new critical quality attributes need to be carefully monitored from developability in early phases and then during process development and clinical phases...
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FDA approves automated insulin delivery and monitoring system for paediatric patients
The FDA has approved a diabetes management device that is intended to automatically monitor glucose and provide appropriate basal insulin doses with little or no input from the user...
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Implantable device delivers drugs straight to the heart
Device can deliver drugs, proteins and stem cells directly to diseased tissue...
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Mechanotargeting may open the door to better cancer drug delivery
Bioengineers may be able to use the unique mechanical properties of diseased cells, such as metastatic cancer cells, to help improve delivery of drug treatments to the targeted cells...
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Aptar Pharma and Propeller Health partner to develop digital medicine platform across therapeutic areas
Collaboration also includes strategic investment by Aptar Pharma; will add connectivity to drug-delivery routes to improve adherence and treatment outcomes...
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AIBP injection alleviates chemotherapy pain for months in mice
Protein inhibits inflammatory response underlying chronic pain processing may provide an alternative to opioids for severe, persistent pain...
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Drug-delivering nanoparticles could help fight brain cancer
Nanoparticles carrying two drugs can cross the blood-brain barrier and shrink glioblastoma tumours...
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Bacteria therapy shows promise for eczema
Topical treatment with live Roseomonas mucosa was found to be safe for adults and children with atopic dermatitis...
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Delivering cancer treatment on a nanodisc helps eliminate tumours
Novel platform for chemo-immunotherapy eliminated colon cancer in 85 percent of treated mice...
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Flare-responsive hydrogel developed to treat arthritis
Researchers develop a better delivery system for anti-inflammatory therapies...
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Injectable MDP-hydrogel may help heal diabetic ulcers
Researchers have created a hydrogel that is capable of helping the body heal and that may also be particularly good at treating wounds related to diabetes...
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T-VEC treatment shows promise for treating advanced stage liver tumours
Phase 1 data supports the use of image-guided therapy for difficult to treat cancer...
