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No Doubts with your drug development
Cross checking your HPLC method for impurity profiling with TLC.
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HPLC
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Application Note: Real time, low flow, pharmaceutical soil cleanability profiling with TOC and conductivity
Designing a robust cleaning process for pharmaceutical drug manufacturing is critical to successful cleaning validation and verification.
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Scientific Poster: How complementary chromatographic methods can support a full analytical picture in pharmaceutical drug development
HPLC is a rapid, accurate and sensitive method for determination of pharmaceutical drugs, degradations and impurity profiling. It is a preferred method for analytical characterisation during drug development.
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Application Note: Streamlined purification of assay‑ready oligonucleotides by automated HPLC
Oligonucleotides must be of high purity when used in molecular biology applications, but efficient purification over a large range of production scales is challenging. The Gilson GX-271 Oligonucleotide Purification System provides a versatile solution for continuous separation, analysis, and desalting of oligonucleotides...
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Application Note: Cost-effective approach to the purification of cannabinoids using CPC
Chromatographic purification of natural compounds presents many challenges to scientists because of the complex nature of the starting matrices that are used in the process...
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Application Note: Analytical vs Preparative HPLC: what’s the difference?
The advent of High Performance Liquid Chromatography (HPLC) has revolutionised analytical chemistry, greatly enhancing not only the speed of column chromatography, but also the separation and identification capacity of analytes...
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Understanding current CFR 21.11 and data integrity requirements
8 August 2018 | By SUEZ
The US FDA and European Commission have defined regulations relating to the submission of electronic records in lieu of paper documents, for submission, inspection, and archiving purposes. When ageing analytical equipment is to be replaced 21CFR Part 11 and EU Annex 11 are also topics of discussion. Common questions from…
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Overcoming unusual challenges in the characterisation of a monoclonal antibodies by LC-MS from early to late stage of development
2 July 2018 | By SCIEX
Different modalities of monoclonal antibodies are pushing the limits of characterization by MS: new critical quality attributes need to be carefully monitored from developability in early phases and then during process development and clinical phases...
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Waters new ACQUITY UPLC PLUS Series sets new performance benchmarks
Next-Generation UPLC Platform designed to keep pace with evolving laboratory requirements for chromatographic performance...
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Watson-Marlow Fluid Technology Group presenting complete bioprocessing fluid path showcase at INTERPHEX 2018
Visit Booth 2833 to see how Watson-Marlow Fluid Technology Group is able to work with you at every process step...
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Gilson’s combined GX-241 Liquid Handler and PLC Purification Systems offer increased sample throughput with less manual intervention
Gilson, an industry leader in liquid handling systems, now offers the GX-241 Liquid Handler as an optional autosampler to its reliable PLC 2050 and PLC 2250 Purification Systems. The GX-241 Liquid Handler provides automated sample injection, increasing throughput and decreasing hands-on time...
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Interview: KNAUER’s dedicated Sugar Analytics HPLC System
Kate Monks, Head of Application & Academy at KNAUER, explains at the HPLC 2017 meeting in Prague the application areas and customer benefits of the new AZURA® Sugar Analytics HPLC System.
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Interview: KNAUER’s Online SPE System
Kate Monks, Head of Application & Academy at KNAUER, explains at the HPLC 2017 meeting in Prague the specially developed AZURA® HPLC system for solid phase extraction (SPE) to automate the sample preparation.
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Merck Introduction video
Merck, which operates as MilliporeSigma in U.S. and Canada, is proud to present their extended portfolio and innovations across the HPLC workflow. Visit SigmaAldrich.com/Brighter
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Chromolith WidePore 300
Revolutionary monolithic column technology is now available for large molecule separations; Chromolith® WidePore 300 has different functionalizations to meet chromatographic needs for pharma research.
