Microbiology In-Depth Focus 2018

This issue features articles on Burkholderia cepacia complex, culturomics and metagenomics, and evaluation of microbiological purified water trend using two types of control chart.

Continuous Manufacturing In-Depth Focus
  • Burkholderia cepacia complex: review of origins, risks and test methodologies
    Burkholderia cepacia complex (BCC) isolates are causes of healthcare-associated infection, especially in relation to contamination of aqueous inhalers and some intravenously administered products. The bacterial species can cause opportunistic infections in vulnerable individuals, especially those with cystic fibrosis (CF). The organisms can cause pneumonia in immunocompromised individuals (especially when introduced into the air passages of a susceptible population).
  • Learning from clinical microbiologists – culturomics and metagenomics
    In recent years there has been significant interest in the sequencing of the human microbiome and what can be learned from this project. One particular area of interest is those normally occurring microorganisms in the human gut.
  • Evaluation of microbiological purified water trend using two types of control chart
    The microbial population in water is dynamic and may change not only from day to day but also at different times of the day. Researchers have observed that this microbiological distribution usually follows the Poisson or Negative Binomial model.

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