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Paul Royall

 

article

Quality control of freeze-dried oral formulations; challenges when developing novel approaches for the delivery of poorly-soluble drugs

22 August 2017 | By ,

A common obstacle encountered in the early stages of drug development is the formulation of poorly water-soluble drugs (PWSDs). One effective approach to improve the dissolution of PWSDs is to render such drugs into their amorphous or disordered form. However, amorphous materials are both physically and chemically unstable, and tend…

reference

Courtney P et al. Freeze-dried formulations: a new perspective on reformulating naloxone. European Pharmaceutical Review. 2017;3:32-36

12 July 2017 | By , , , ,

References National Institute on Drug Abuse: Overdose Death Rates, https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/national-overdose-deaths2015.pdf (Accessed 24 February 2017) www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2015/estimated-deaths-for-the-four-major-cancers-by-sex-and-age-group-2015.pdf Strang J, Bird SM, Parmar MKB. Take-Home Emergency Naloxone to Prevent Heroin Overdose Deaths after Prison Release: Rationale and Practicalities for the N-ALIVE Randomized Trial. Journal of Urban Health-Bulletin of the New York Academy of…