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David Keller

 

Non-clinical dose formulation considerations

Designing appropriate non-clinical safety studies requires thoughtful, and sometimes experimental,…

15 December 2017 | By

Designing appropriate non-clinical safety studies requires thoughtful, and sometimes experimental, consideration of the delivery methodology for the therapeutic. The choice of formulation affects drug release and absorption and has a direct impact on the pharmacokinetic profile and associated response of the model system. The formulation should be compatible with the…