Pharma Horizons: Formulation

 Successful formulations can enhance the stability, bioavailability and performance of a drug product, while also improving patient usability. The final drug product comprises the active pharmaceutical ingredient (API), excipients and, where applicable, a coating, which can each influence the product’s properties and therapeutic performance. Selecting an appropriate formulation therefore involves multiple steps to ensure it is optimal, scalable and compliant with regulatory requirements.

This report will explore the latest advances in drug formulations, from nanotechnology and lipid delivery systems to bioavailability-enhancing excipients and advancements in lyophilisation. This report will also explore the key challenges in pharmaceutical formulation development, from selecting the most appropriate formulation technologies and identifying risks early in development to ensuring successful scale-up, manufacturing and regulatory compliance. It will also examine the critical role of quality control in delivering robust, commercially viable formulations.

Inside this report you’ll discover:

• Understand the key challenges in pharmaceutical formulation development, scale-up and manufacturing
• How to identify and mitigate risks early in development to select the most appropriate formulation strategy and technologies
• The challenges facing oral dosage form development and what is required to achieve consistent performance during scaleup
• How advances in excipient and coating technologies and beyond can help formulators develop robust and effective drug products
• How increasingly complex small molecule candidates are changing formulation development to support scalability, manufacturability and commercial viability
• How excipient and coating technologies can help address the formulation challenges of increasingly complex molecules, including peptides and ADCs
• How predictive modelling and digital tools can support earlier assessment of developability and formulation risk
• Discover how the right formulation strategy can support successful scale-up, manufacturability and the delivery of robust, commercially viable products. 

Download the report to explore some the issues at the forefront of pharmaceutical industry discussions around pharmaceutical formulation from European Pharmaceutical Review >>