webinar

Don’t let difficult substances control your cleaning validation

Supported by:

29 May 2019

Supported by:

29 May 2019

SUEZ

TOC analysis is a widely adopted method for detecting residual product or cleaning agents on manufacturing equipment. Compared to specific methods such as HPLC, TOC can provide better process understanding and efficiency for cleaning validation (CV), verification and continuous monitoring.

Some products have complicated organic structures and/or are difficult to oxidise, such as proteins and high molecular weight compounds. For these challenging applications, it may be necessary to consider different TOC vial types and perform recovery studies to determine suitability. While some substances are difficult, it doesn’t always mean they can’t be recovered.

Watch this webinar on-demand to hear examples of best practices for performing TOC recovery studies for cleaning validation applications, including comparison of pre-acidified and non-acidified vials. Learn how to take control and detect difficult substances.

Register

Register to watch this on-demand webinar















    Unless making a secure payment with your credit or debit card via a third-party payment processor, this form is not designed to collect confidential or sensitive personal information (e.g., financial information, social security numbers).

    *Required field

    Your details


    *

    *

    *

    *

    *


    *

    Email preferences

    If you're not already opted-in to receive our emails, please select which types of communication you would like to receive:


    Confirm that you're human

    By clicking register, you consent to European Pharmaceutical Review contacting you about this and future webinars, and that you agree to our terms and conditions and privacy policy. Your information will be processed in accordance with GDPR and you can unsubscribe at any time.

    Speakers

    Daniel Kellner-Steinmetz, EMEA Application Lead UPW/CV, SUEZ 

    Daniel Kellner-SteinmetzDaniel Kellner-Steinmetz is the EMEA Applications Specialist for SUEZ, focussing on Life Science UPW and Cleaning Validation applications. He has eight years of experience in the quality, manufacturing and training areas of the pharmaceutical industry. Most recently he served as the Global Product Quality Lead for several commercial products at Shire (formerly Baxter) in Vienna. Daniel holds a Bachelor of Science in Biomedical Engineering.

    Key learning points

    • Challenges of difficult-to-recover compounds in cleaning validation applications
    • Examples of TOC recovery studies and best practices
    • Comparison of acidified and non-acidified vials for recovery studies
    • How to make dilutions, test and evaluate resultant data for recovery and linearity
    • Other considerations using TOC for CV.

    Send this to a friend