This study details the use of the new Scale Up Assist feature of the BioFlo 720 Bioreactor Control System to scale CHO batch cultures.
This study details the use of the new Scale Up Assist feature of the BioFlo 720 Bioreactor Control System to scale CHO batch cultures from 3 L over 10 L stirred-tank, rigid-wall BioBLU® Single-Use Bioreactors (SUBs) to either 50 L or 250 L stirred SUB-bags. Using a built-in constant power software algorithm, the Scale Up Assist specified what agitation and gassing set points to use for different vessel sizes.
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