Application note: Workflow for antibody aggregate and fragment analysis
Posted: 14 December 2022 | Merck | No comments yet
A complete SEC-UV workflow has been developed to enable quantitative analysis of antibody fragments and aggregates. In detail, it includes:
- Procedure for heat stressing of antibodies
- System suitability test utilising a gel filtration standard
- SEC-UV method for sample separation and analysis.
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Analytical techniques, Biopharmaceuticals, Formulation, Manufacturing, QA/QC, Research & Development (R&D)