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Raman spectroscopy has been successfully integrated in laboratory, pilot, process development and GMP manufacturing environments. Find out how it was used at the pilot scale to detect the endpoint of a heterogeneous etherification reaction...
This application note discusses an application of Raman spectroscopy for real-time, non-destructive evaluation of chemical changes in the API...
This application note describes a proof of the concept that enhanced Raman reflection spectroscopy can generate strong Raman signal from throughout the depth of a sample....
This application note presents a cross-scale application as a follow-up to the process development study reported in Kaiser Application Note: Analysis of a Mammalian Cell Culture...
This application note demonstrates the suitability of Raman spectroscopy using Kaiser’s PhAT technology to monitor active coating...
This application note explains how in situ Raman can improve process knowledge and ensure an efficient process that consistently makes quality product safely...
In this application note, Kaiser Optical Systems, Inc. discuss raman-based nutrient control in bioprocessing...
In this application note, find out more about the RamanRxn1™ High Throughput Screener (HTS) from Kaiser Optical Systems, Inc...
This Kaiser application note focuses on real-time, in situ process understanding using a Raman-based PAT approach. Raman spectroscopy is uniquely useful for biotechnology ‘Quality by Design’ (QbD) applications because it enables fast, non-destructive monitoring and control...
Find out how recent advances in technology have made Raman spectroscopy better and more affordable for polymer analysis than traditional IR spectroscopy...
In mammalian-cell-based bioprocesses the most common critical process parameters (CPPs) include physical parameters (temperature, pressure, dissolved oxygen [DO] levels) as well as chemical properties (pH, concentrations of both substrates and byproducts) and biochemical properties (cell number and viability, cell physiology).
Many organic compounds can crystallize in several different forms called polymorphs. Biologically active polymorphs have different solubility and stability and, hence, different bioavailability. The effectiveness of a drug compound depends critically on its particular polymorph.
Raman monitoring of blended granule uniformity prior to tablet press...
This note describes the use of enhanced Raman reflection spectroscopy to accomplish analysis on multi-layered samples similar to many pharmaceutical tablets...
This application note demonstrates the suitability of Raman spectroscopy using Kaiser’s unique noncontact large-spot PhAT technology to monitor of active coating composition.
