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CPC – Ideal for your natural product purification
Centrifugal partition chromatography (CPC) is a silica-free method, using two immiscible liquids as stationary and mobile phases...
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Issue 6, 2018
In this issue: Navigating roadblocks to clinical success: decision-making from molecule to clinic, Raman spectroscopy for the qualitative analysis of falsified and substandard medicines, and an overview of risk assessments for elemental impurities: implementation of ICH Q3D guidelines.
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Ensuring supplier and compounded drug quality
It is paramount that manufacturers and their suppliers ensure that the quality of compounded drugs are high, by preventing risks of contamination...
whitepaper
Application Note: Tracking fate and purge of impurities and calculating carryover
The purpose of process development in pharma is to select and optimise a synthetic route to produce the active pharmaceutical ingredient (API) by the safest, cheapest, fastest, and cleanest (by green chemistry where possible) route, following both Good Laboratory Practice (GLP) and Quality by Design (QbD) principles.
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Discovery to save more women in childbirth from postpartum hemorrhaging
The development of a drug that could be used to save women from postpartum hemorrhaging, could save many thousands of women each year...
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Using graphene as a tunable ion filter
NIST researchers have shown how graphene can be modified with pores and used as an ion filter, and could be adapted for use in drug delivery systems...
whitepaper
Whitepaper: Ten things you should know before contracting a custom synthesis project
Companies often need to arrange for the synthesis of test substances to support research and development efforts.
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Strong spending seen in US medical and health R&D over five-year period
The pharmaceutical industry accounted for 67 percent of the total spending on research and development, with federal government accounting for 22 percent...
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Paul DiMarco introduces BioSpectra as your provider of critical small molecule excipients and APIs
BioSpectra offers US based, custom GMP manufacturing of small molecules...
whitepaper
Application Note: Streamlined purification of assay‑ready oligonucleotides by automated HPLC
Oligonucleotides must be of high purity when used in molecular biology applications, but efficient purification over a large range of production scales is challenging. The Gilson GX-271 Oligonucleotide Purification System provides a versatile solution for continuous separation, analysis, and desalting of oligonucleotides...
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2018 JRS PHARMA News!
JRS Pharma is a leading manufacturer of excipients, offering a complete portfolio of excipient solutions for the pharmaceutical and nutraceutical industries...
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Solid-state NMR spectroscopy: predicting stability in lyophilised biological products
The emergence of biological drugs has led to an increase in lyophilised drug products in the market. Lyophilisation is a technique used to stabilise parenteral formulations in a solid form with the goal of producing chemically and physically stable, homogeneous, and high-quality lyo-products.
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Medical cannabis made available on prescription in the UK
Medical cannabis is now avaliable through the NHS, but many are warning about its drawbacks and that it won't be available for those who need it...
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‘Booming’ pharmaceutical industry in Scotland
A report conducted by the University of Strathclyde has revealed that the pharmaceutical market in Scotland is booming with over £462m in exports...
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Evaluation of microbiological purified water trend using two types of control chart
The microbial population in water is dynamic and may change not only from day to day but also at different times of the day. Researchers have observed that this microbiological distribution usually follows the Poisson or Negative Binomial model.1
