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chronic heart failure

Novo Nordisk to buy Cardior Pharmaceuticals

25 March 2024 | By Caroline Peachey (European Pharmaceutical Review)

The up to €1bn acquisition of Cardior Pharmaceuticals will strengthen Novo Nordisk’s pipeline in cardiovascular disease.

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Boehringer plans €120m European manufacturing expansion

12 January 2024 | By Catherine Eckford (European Pharmaceutical Review)

The manufacturing capacity for some of Boehringer Ingelheim’s medicines, in disease areas including mental health and cardio-renal-metabolic conditions, will benefit from the European facility expansion.

news

AstraZeneca’s tezepelumab and dapagliflozin accepted for use in Scotland

8 August 2023 | By Catherine Eckford (European Pharmaceutical Review)

The Scottish Medicines Consortium (SMC)’s acceptance means eligible patients across the UK can now benefit from AstraZeneca's Tezspire (tezepelumab) for severe asthma and Forxiga (dapagliflozin) for chronic heart failure.

news

New CKD treatment option approved in EU

26 July 2023 | By Catherine Eckford (European Pharmaceutical Review)

The first SGLT2 inhibitor to demonstrate a statistically significant reduction in all-cause hospitalisations in chronic kidney disease (CKD) patients versus placebo has been approved in the EU.

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First NICE-recommended treatment for chronic heart failure

19 May 2023 | By Catherine Eckford (European Pharmaceutical Review)

In final draft guidance, the National Institute for Health and Care Excellence (NICE) has recommended dapagliflozin (Forxiga) for patients with heart failure regardless of ejection fraction.

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Recent developments in stem cell therapies

16 May 2023 | By Catherine Eckford (European Pharmaceutical Review)

EPR explores recent developments in stem cell therapies across several hard-to-treat diseases and how technology is transforming ATMP manufacture.

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Cell therapy first for chronic heart failure

28 February 2023 | By Catherine Eckford (European Pharmaceutical Review)

In a Phase III trial, a new cell therapy has shown potential for the first time to treat inflammation, a major contributor to heart failure.

news

Forxiga approved in EU for chronic heart failure

7 February 2023 | By Catherine Eckford (European Pharmaceutical Review)

Forxiga (dapagliflozin) has been approved in the EU for chronic heart failure across the full spectrum of left ventricular ejection fraction.

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Dapagliflozin approved for heart failure across LVEFs

12 December 2022 | By Catherine Eckford (European Pharmaceutical Review)

The MHRA has approved dapagliflozin for chronic heart failure across the full spectrum of left ventricular ejection fraction.

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EMA’s human medicines committee (CHMP) meeting highlights, May 2021

24 May 2021 | By Hannah Balfour (European Pharmaceutical Review)

In its latest meeting the CHMP recommended eight medications for approval, 17 medicines for indication extension and concluded reviews of two COVID-19 treatments.

3D rendering of embryonic stem cells in red and orange with purple nuclei - idea of curative cell therapies

article

Curative cell and gene therapies and healthcare system disruption

20 May 2021 | By Anna Hillel (Charles River Associates), Artes Haderi (Charles River Associates), Rebecca Steele (Charles River Associates)

In this article, experts from Charles River Associates discuss how the introduction of cell and gene therapies will impact upon various aspects of the healthcare system, from provision of care to delivery and supply, and pricing and market access.

news

Primary endpoint met in drug study for worsening chronic heart failure

19 November 2019 | By Rachael Harper (European Pharmaceutical Review)

A study evaluating the efficacy and safety of vericiguat, a treatment for patients with worsening chronic heart failure, has met the primary efficacy endpoint.

news

Heart failure therapy for patients with acute illness

13 November 2018 | By European Pharmaceutical Review

Yale-led research has shown how sacubitril-valsartan improves markers of poor prognosis in individuals who are hospitalised with acute heart failure...

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