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Immunotherapy combo could overcome melanoma anti-PD-1 resistance
A “practice-changing” immunotherapy drug combination demonstrated inhibition of two main immune checkpoints in a trial assessing efficacy in metastatic melanoma.
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Metastatic melanoma
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Re-engineering proteins to develop novel immunotherapies
Jessicca Rege of Alkermes provides insights into how protein engineering approaches have led to the development of novel therapies that harness the immune system’s capabilities to fight cancer.
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Personalised cancer immunotherapy granted fast track designation
The FDA has granted fast track designation for Evaxion’s personalised cancer vaccine in combination Keytruda® for patients with metastatic melanoma.
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Achilles Therapeutics expands manufacturing in the UK
The scale up in annual capacity and expansion of Achilles' global clinical manufacturing footprint will see its second site in the UK and first site to be established in the US.
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Metastatic melanoma treatment gets Breakthrough Therapy Designation
Breakthrough Therapy Designation has been granted for investigational agent bempegaldesleukin in combination with nivolumab.
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Genetically modified viral injection could treat metastatic melanoma
A study has reported that almost 40 percent of patients with non-surgically treatable tumours were effectively treated using a genetically modified virus...
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Combining drugs that target BRAF and HSP90 shows success for melanoma patients
Scientists have tried combining drugs in an effort to prevent resistance development that eventually leads to cancer regrowth in melanoma patients.
