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metastatic triple-negative breast cancer (mTNBC)

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AstraZeneca and Daiichi’s Datroway gets phase III breast cancer boost

6 October 2025 | By Dominic Tyer (European Pharmaceutical Review)

Companies’ first-line ambitions for the antibody drug conjugate buoyed by the TROPION-Breast02 clinical trial.

article

France’s ATU reform: early access remains possible, but not all diseases are equal

6 December 2022 | By Cécile Matthews (CRA), Charlotte Capdevila

When France's ATU reform was implemented, some viewed it as restrictive. Here, Cécile Matthews and Charlotte Capdevila explore the reform’s impact on early access to oncology drugs and products for rare diseases.

article

Merck’s Keytruda^®: update on trials and outcomes

8 October 2021 | By Anna Begley (European Pharmaceutical Review)

EPR’s Anna Begley summarises some of the key results from trials of Merck’s Keytruda® (pembrolizumab) cancer treatment.

Doctor with mammograph, indicating breast cancer

news

Trodelvy^® improves breast cancer survival and quality of life

17 September 2021 | By Anna Begley (European Pharmaceutical Review)

Trodelvy significantly improved overall survival and demonstrated clinically meaningful improvements in quality of life in Phase III study.

news

EMA’s human medicines committee (CHMP) meeting highlights, May 2021

24 May 2021 | By Hannah Balfour (European Pharmaceutical Review)

In its latest meeting the CHMP recommended eight medications for approval, 17 medicines for indication extension and concluded reviews of two COVID-19 treatments.

Red CAR T cells attacking a central larger white 'cancer' cell on a dark turquoise background - idea of CAR T-cell therapy

news

First-in-human universal CAR-T therapy trial begins

4 December 2020 | By Hannah Balfour (European Pharmaceutical Review)

The dose-finding trial will evaluate the safety and activity of UniCAR-T-PSMA in up to 16 patients with advanced relapsed/refractory, PSMA-positive solid tumours.

news

Gilead Sciences to acquire Immunomedics for $21 billion

17 September 2020 | By Victoria Rees (European Pharmaceutical Review)

Gilead is set to acquire Immunomedics for approximately $21 billion, with the transaction anticipated to close in the fourth quarter of 2020.

news

Keytruda^® (pembrolizumab) with chemotherapy meets Phase III PFS endpoint

18 February 2020 | By Hannah Balfour (European Pharmaceutical Review)

The drug’s developers reveal Keytruda increased progression-free survival (PFS) in patients with metastatic triple-negative breast cancer (mTNBC) expressing PD-L1.

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metastatic triple-negative breast cancer (mTNBC)