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Oncology

Sanofi to sell Japanese manufacturing plant

17 October 2022 | By Catherine Eckford (European Pharmaceutical Review)

Sanofi’s Japan-based manufacturing site near Tokyo will be sold to a European contract development and manufacturing organisation.

article

Issue #6 2016 – Digital version

13 December 2016 | By European Pharmaceutical Review

Read the free-to-view digital version of the latest issue of European Pharmaceutical Review...

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ESMO 2016: New data from Eisai’s oncology portfolio for halaven (eribulin), lenvima (lenvatinib) and kisplyx (lenvatinib)

4 October 2016 | By Niamh Louise Marriott, Digital Content Producer

European Pharmaceutical Review will of course keep you up to date with all the latest pharma news from the conference. Here's a preview snippet...

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Bristol-Myers Squibb and Nektar Therapeutics to combine oncology therapies

28 September 2016 | By Niamh Louise Marriott, Digital Content Producer

Bristol-Myers' Opdivo is a PD-1 immune checkpoint inhibitor designed to overcome immune suppression and NKTR-214 is an immuno-stimulatory therapy...

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Initiation of HTL1071 trial triggers $10m payment to Heptares

6 July 2016 | By Victoria White, Digital Content Producer

The first subject has been dosed with immuno-oncology candidate HTL1071 in a Phase I clinical study, triggering a US$10 million payment to Heptares...

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Positive results for Yeliva in Phase I advanced solid tumour study

4 July 2016 | By Victoria White, Digital Content Producer

Yeliva is a first-in-class, orally-administered sphingosine kinase-2 (SK2) selective inhibitor with anticancer and anti-inflammatory activities...

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Xilonix demonstrates significant clinical response in colorectal cancer study

4 July 2016 | By Victoria White, Digital Content Producer

XBiotech’s Xilonix is the first monoclonal antibody immunotherapy to specifically target and neutralise interleukin-1 alpha (IL-1α)...

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BMS and PsiOxus to evaluate Opdivo and enadenotucirev in cancer

1 July 2016 | By Victoria White, Digital Content Producer

The companies are to evaluate the safety, tolerability and efficacy of enadenotucirev and Opdivo in a range of tumour types in late-stage cancer patients...

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Global urological cancers market to double by 2022, says GBI Research

30 June 2016 | By Victoria White, Digital Content Producer

The urological cancers market will increase from $17.9 billion in 2015 to $35.9 billion by 2022, according to business intelligence provider GBI Research...

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Regorafenib increases overall survival in hepatocellular carcinoma study

29 June 2016 | By Victoria White, Digital Content Producer

Results from the Phase III RESORCE trial investigating Bayer’s regorafenib in patients with unresectable hepatocellular carcinoma have been announced...

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Novartis and Xencor enter bispecific antibody collaboration

28 June 2016 | By Victoria White, Digital Content Producer

The collaboration includes XmAb Bispecific Technology for 4 Novartis targets and access to Xencor Fc Technologies...

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Cancer immunotherapy drugs linked to autoimmune diseases

24 June 2016 | By Victoria White, Digital Content Producer

Some cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at a higher-than-normal risk of developing autoimmune diseases...

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Phase I/II trial of INCAGN1876 in solid tumours starts

22 June 2016 | By Victoria White, Digital Content Producer

The open-label, dose-escalation portion of the trial will evaluate the safety and tolerability of INCAGN1876 in patients with solid tumours...

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Denosumab may prevent breast cancer in women with BRCA1 gene mutation

20 June 2016 | By Victoria White, Digital Content Producer

Researchers have discovered that an existing medication, denosumab, may prevent breast cancer in women carrying a faulty BRCA1 gene...

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Chemo may boost immunotherapy power in ovarian cancer

15 June 2016 | By Victoria White, Digital Content Producer

A study has found that women with ovarian cancer may benefit more from immunotherapy drug treatments if they are given straight after chemotherapy...

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Oncology