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Evofosfamide fails in two late-stage cancer trials
7 December 2015 | By Victoria White
Merck KGaA will also not be pursuing the treatment in pancreatic adenocarcinoma after the drug failed in two late-stage clinical trials...
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Oncology
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Personalised peptide vaccine increased bladder cancer survival in study
18 November 2015 | By Victoria White
The median overall survival for patients assigned personalised peptide vaccine and best-supportive care was almost twice as long as that for patients assigned best-supportive care...
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Black Swan Analysis short-listed for the TVBM 2015 Management Team of the Year Award
3 November 2015 | By Black Swan Analysis
Black Swan Analysis has just been short-listed for the “The Management Team of the Year Award” sponsored by NatWest and open to outstanding management teams in the Thames Valley...
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Phase 3 trial of Adcetris in Hodgkin lymphoma completes target enrolment
27 October 2015 | By Victoria White
Data from a Phase 1 trial evaluating Adcetris plus AVD demonstrated that 24 of 25 patients (96 percent) achieved a complete remission...
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AstraZeneca and Lilly expand immuno-oncology collaboration
22 October 2015 | By Victoria White
Under the terms of the expanded agreement, AstraZeneca and Lilly will evaluate the safety and efficacy of a range of additional combinations across the companies’ portfolios...
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Crowdfunding bid to test malaria drug in cancer
16 October 2015 | By Victoria White
Scientists investigating whether the malaria drug artesunate could have a significant impact on colorectal cancer have launched a crowdfunding project to fund their work...
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Data on Eisai’s eribulin and lenvatinib presented at DGHO
13 October 2015 | By Victoria White
Five abstracts have highlighted the use of Eisai’s eribulin and lenvatinib in rare cancers at the German Association of Hematology and Oncology Meeting...
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Merck and DNAtrix announce glioblastoma collaboration
2 October 2015 | By Victoria White
Merck and DNAtrix will evaluate the efficacy and safety of DNX-2401 in combination with Keytruda in a Phase 2 study...
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Advanced targeted therapies dominate colorectal cancer pipeline
29 September 2015 | By Victoria White
Advanced targeted therapies now account for 60% of the drugs under development for colorectal cancer...
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Aspirin improves survival in gastrointestinal cancer
28 September 2015 | By Victoria White
The results of the study, involving nearly 14,000 patients, may lead to new insights regarding the use of aspirin in gastrointestinal cancer...
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Verastem stops enrolment in trial of VS-6063 in mesothelioma
28 September 2015 | By Victoria White
While VS-6063 had a generally well tolerated safety profile, there was not a sufficient level of efficacy to warrant continuation of the study...
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AstraZeneca in bioinformatics collaboration with University of Manchester
9 September 2015 | By Victoria White
AstraZeneca and The University of Manchester are teaming up to harness clinical bioinformatics to deliver personalised healthcare for cancer patients...
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Aspirin reduces obesity-associated cancer risk
18 August 2015 | By Victoria White
An international study of people with a family history of cancer has shown that a regular dose of aspirin reduces the long-term risk of the disease...
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Phase 1/2 trial of Mogamulizumab and Opdivo in advanced solid tumours announced
30 July 2015 | By Victoria White
Kyowa Hakko Kirin and Bristol-Myers Squibb are to conduct a Phase 1/2 combination study with mogamulizumab and Opdivo in advanced solid tumours...
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PLX3397 demonstrates prolonged tumour regression in TGCT
30 July 2015 | By Victoria White
Clinical trial results demonstrate that PLX3397 induced prolonged tumour regressions in most patients with tenosynovial giant cell tumour (TGCT)...
