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Alice Harrison (Lonza)

 

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Optimising bispecific antibody clonal cell selection with high-throughput analytics

It is possible to manufacture monoclonal antibodies using traditional methods,…

22 December 2022 | By ,

It is possible to manufacture monoclonal antibodies using traditional methods, but the challenges inherent in bispecific antibodies such as low titer, mismatched chains, unwanted fragments and higher aggregation levels require a heightened analytical focus on clonal cell selection. Here, Stuart Jamieson and Alice Harrison at Lonza discuss high-throughput analytical strategies…