Video: More efficient Cleaning Validation with Sievers TOC
TOC analysis in the lab, at-line, or online enables efficiency gains and process understanding for cleaning validation and monitoring programs.
Sievers TOC Analyzers with membrane conductometric technology are used to accurately measure organics in rinse and online samples for cleaning validation. The Sievers M9 reports validated and accurate TOC data in addition to simultaneously quantifying inorganic carbon and conductivity. Together, these data provide a comprehensive understanding of a cleaning process.
Compared to specific methods, TOC offers simpler method development and allows not only for testing to confirm product / API removal, but also removal of excipients, degradants, and cleaning agents. Sievers TOC Analyzers can be deployed in the lab, at-line, or online integrated directly onto a Clean-In-Place (CIP) skid.