App Note: Following the progress of pharmaceutical mixing studies using near-infrared spectroscopy
This free-to-view Application Note shows the possibility to apply near-infrared spectral information for monitoring the pharmaceutical mixing process…
One of the most arduous, yet important steps in solid dosage form development is the mixing study. In most dosage form development standard operating procedures (S.O.P.s), the mixer is charged (loaded with the excipients and actives), then mixed for a set time (5, 10, 15 minutes). The mixer is opened and a “sample thief” is used to obtain “grab” samples from various locations and depths throughout the mixer. The mixer is closed and operated for the next time period. A series of samples representing the uniformity of the mixer’s contents is collected and sent to the analytical lab for analysis.
This whitepaper is restricted - login or subscribe free to access
Thank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.
Why subscribe? Join our growing community of thousands of industry professionals and gain access to:
- bi-monthly issues in print and/or digital format
- case studies, whitepapers, webinars and industry-leading content
- breaking news and features
- our extensive online archive of thousands of articles and years of past issues
- ...And it's all free!
Related content from this organisation
- Metrohm acquires innovative Photonic Solutions to expand Handheld Raman portfolio
- Application Notes & Whitepapers 2017
- Whitepaper: Do you know what’s going in? Analysing tablets by NIR spectroscopy
- Whitepaper: Regulatory compliance in pharma – software requirements and solutions
- Metrohm & CAMO Software are announcing a global partnership