Application Note: MALDI-ToF Mass Spectrometry – A valid alternative for microbial identification
MALDI-ToF mass spectrometry, a phenotypical RMM for microbial identification, is a unique, highly accurate alternative method that facilitates cost-effective, precise and rapid data acquisition.
Rapid and accurate identification of pathogenic microorganisms in areas such as pharmaceutical and medical device manufacturing are of paramount importance. Traditional identification techniques often require subcultures on selective medium, colony isolation, Gram staining or biochemical testing, which are labour intensive and time consuming.
Rapid microbiological methods (RMMs) for microbial identification have been widely adopted by the clinical microbiology environment due to their speed and accuracy resulting in reduced risk and improved patient safety. Furthermore, as RMMs generally reduce product release cycle time, labour and cost alongside supporting real-time data analysis and high throughput, it is unsurprising that these technologies are also being adopted by the pharmaceutical and medical device industries.
Matrix Assisted Light Desorption Ionisation Time-Of Flight (MALDI-ToF)
MALDI-ToF mass spectrometry, a phenotypical RMM for microbial identification, is a unique, highly accurate alternative method that facilitates cost-effective, precise and rapid data acquisition. Since its introduction by Karas and co-workers in 1987, MALDI-ToF mass spectrometry has been substantially developed and is now considered to be a real alternative for bacterial identification due to the provision of rapid and specific determination analogous to molecular sequencing techniques, with the benefit of significant time and cost savings.
This application note is restricted - login or subscribe free to access
Thank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.
Why subscribe? Join our growing community of thousands of industry professionals and gain access to:
- bi-monthly issues in print and/or digital format
- case studies, whitepapers, webinars and industry-leading content
- breaking news and features
- our extensive online archive of thousands of articles and years of past issues
- ...And it's all free!
Related content from this organisation
- Wickham Laboratories to exhibit at Making Pharmaceuticals UK 2018
- Wickham Labs to exhibit at inaugural Making Pharmaceuticals Europe Conference 2018
- Wickham Laboratories Holdings announces Planning Application approval
- Application Notes & Whitepapers 2017
- Rapid testing methods: the cost-effective safety solution